Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | KCNA2 | P16389 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopimpinellin SCHEMBL498907 | 0.84 | CYP3A4 (1.00) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| Isopimpinellin SCHEMBL29568822 | 0.84 | CYP3A4 (1.00) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL434686 | 0.80 | CYP3A4 (0.80) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL31542614 | 0.80 | CYP3A4 (0.80) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| Pimpinellin SCHEMBL2255899 | 0.77 | CYP3A4 (1.00) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL5960652 | 0.77 | CYP3A4 (0.74) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2383938 | 0.77 | CYP3A4 (0.74) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL6200404 | 0.77 | CYP3A4 (0.74) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| Pimpinellin SCHEMBL29162721 | 0.76 | CYP3A4 (0.97) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 | |
| Isopimpinellin SCHEMBL29787210 | 0.75 | CYP3A4 (0.82) | CYP3A4KDM4ECYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160205925-A1 | ANTIMICROBIAL COMPOSITIONS MADE OF A THERMOPLASTIC POLYMER AND A PHOTOSENSITIZER | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2016-07-21 | — | — | US | disclosed |
| US-20160160178-A1 | IMMUNOTHERAPY USING STEM CELLS | WHITE OAK IND INC (US) | 2016-06-09 | — | — | US | disclosed |
| US-9226917-B2 | Photodynamic therapy for conditions of the eye | VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20150125489-A1 | METHOD FOR THE PREPARATION OF DENDRITIC CELL VACCINES | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2015-05-07 | — | — | US | disclosed |
| US-8968715-B2 | Drug delivery systems for photodynamic therapy | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-03-03 | — | — | US | disclosed |
| EP-2819696-A1 | METHOD FOR THE PREPARATION OF DENDRITIC CELL VACCINES | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2015-01-07 | — | — | EP | disclosed |
| US-8852629-B2 | Drug delivery system for hydrophobic drugs | VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 2014-10-07 | — | — | US | disclosed |
| WO-2013127976-A1 | METHOD FOR THE PREPARATION OF DENDRITIC CELL VACCINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2013-09-06 | — | — | WO | disclosed |
| EP-2600904-A1 | ARTIFICIAL CELLS | Searete LLC (US) | 2013-06-12 | — | — | EP | disclosed |
| US-8211656-B2 | Biological targeting compositions and methods of using the same | THE INVENTION SCIENCE FUND I, LLC (US) | 2012-07-03 | — | — | US | disclosed |
| WO-2002062386-A2 | PHOTODYNAMIC THERAPY OF OCCULT CHOROIDAL NEOVASCULARIZATION LINKED TO AGE-RELATED MACULAR DEGENERATION | QLT INC. (CA) | 2002-08-15 | — | — | WO | disclosed |
| WO-2002062384-A2 | REDUCED FLUENCE RATE PDT | QLT INC. (CA) | 2002-08-15 | — | — | WO | disclosed |
| WO-2002062385-A2 | METHOD TO PREVENT VISION LOSS | QLT, INC. (CA) | 2002-08-15 | — | — | WO | disclosed |
| EP-1229937-A2 | USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA | QLT Inc. (CA) | 2002-08-14 | — | — | EP | disclosed |
| US-20020061330-A1 | Supports for photosensitizer formulations | BRITISH COLUMBIA, THE UNIVERSITY OF (CA) | 2002-05-23 | — | — | US | disclosed |
| US-20020022032-A1 | Immuno-adjuvant PDT treatment of metastatic tumors | QLT INC. (CA) | 2002-02-21 | — | — | US | disclosed |
| WO-2001085213-A2 | SUPPORTS FOR PHOTOSENSITIZER FORMULATIONS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001085212-A2 | DRUG DELIVERY SYSTEMS FOR PHOTODYNAMIC THERAPY | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001035996-A2 | USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA | QLT INC. (CA) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001035997-A2 | USE OF LOW-DOSE PDT TO INHIBIT RESTENOSIS | QLT INC. (CA) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160160178-A1 | IMMUNOTHERAPY USING STEM CELLS | CD14, ICOS, BMP4 | CYP3A4 2073/4885KDM4E 562/4885CYP1A2 4208/4885 |
| US-20020061330-A1 | Supports for photosensitizer formulations | PPOX, PPIF, SDHA | CYP3A4 1095/4885KDM4E 3097/4885CYP1A2 1068/4885 |
| US-20160205925-A1 | ANTIMICROBIAL COMPOSITIONS MADE OF A THERMOPLASTIC POLYMER AND A PHOTOSENSITIZER | CUTA, POLR1C, PUF60 | CYP3A4 1955/4885KDM4E 3572/4885CYP1A2 2124/4885 |
| US-20150125489-A1 | METHOD FOR THE PREPARATION OF DENDRITIC CELL VACCINES | CCR7, CD69, CD14 | CYP3A4 4256/4885KDM4E 3450/4885CYP1A2 4577/4885 |
| US-20020022032-A1 | Immuno-adjuvant PDT treatment of metastatic tumors | CD74, ANXA11, ANXA1 | CYP3A4 3319/4885KDM4E 4361/4885CYP1A2 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.