Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 12/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | NR0B2 | Q15466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709920 | 0.88 | RARB (0.42) | EPHX2PGRRARBRARGRARA | |
| SCHEMBL5000829 | 0.85 | PGR (0.41) | EPHX2PGRCYP3A4PTPN11 | |
| SCHEMBL2709090 | 0.82 | RARB (0.40) | EPHX2PGRRARBRARGRARA | |
| SCHEMBL2709689 | 0.78 | RARB (0.39) | EPHX2PGRRARBRARGRARA | |
| SCHEMBL2710393 | 0.76 | RARB (0.40) | EPHX2PGRRARBRARGRARA | |
| SCHEMBL2708322 | 0.76 | RARB (0.40) | EPHX2PGRRARBRARGRARA | |
| Potassium Ion SCHEMBL5000813 | 0.73 | — | — | |
| SCHEMBL3179396 | 0.73 | RARB (0.37) | EPHX2PGRRARBRARGRARA | |
| SCHEMBL29038978 | 0.72 | PGR (0.55) | EPHX2PGR | |
| SCHEMBL2708058 | 0.72 | EPHX2 (0.36) | EPHX2PTPN11NR0B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337982-B2 | Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance | SUMITOMO BAKELITE CO., LTD. (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20080206548-A1 | Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device | SUMITOMO BAKELITE CO., LTD (JP) | 2008-08-28 | — | — | US | disclosed |
| EP-1832619-A1 | BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Company, Limited (JP) | 2007-09-12 | — | — | EP | disclosed |