Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 2/20 | 0.49 |
| ▸ | ALPP | P05187 | 1/20 | 0.49 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4996791 | 0.84 | CXCR3 (0.57) | SMN1; SMN2NPC1GAARAB9ACA1 | |
| SCHEMBL1818686 | 0.84 | MAPT (0.59) | SMN1; SMN2GAARAB9ATDP1TP53 | |
| SCHEMBL5000979 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2ALPLALPGALPPPLAA | |
| SCHEMBL1802569 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1GAARAB9AALPL | |
| SCHEMBL1801438 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1GAARAB9AALPL | |
| SCHEMBL14470429 | 0.64 | F2R (0.61) | SMN1; SMN2ALPLALPGALPPPLAA | |
| SCHEMBL1803118 | 0.63 | MAPT (0.59) | SMN1; SMN2GAARAB9ATDP1TP53 | |
| SCHEMBL1802857 | 0.63 | CXCR3 (0.57) | SMN1; SMN2NPC1GAARAB9AALDH1A1 | |
| SCHEMBL18426397 | 0.62 | CA1 (1.00) | ALPLALPGALPPPLAATDP1 | |
| SCHEMBL484344 | 0.62 | F2R (0.57) | SMN1; SMN2NPC1RAB9AALPLALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287681-A1 | Substituted Benzimidazoles and their Use for Inducing Apoptosis | EBERLE MARTIN | 2008-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287681-A1 | Substituted Benzimidazoles and their Use for Inducing Apoptosis | BAX, BCL2, BAD | SMN1; SMN2 2693/4885NPC1 3798/4885GAA 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.