Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 4/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818686 | 0.86 | MAPT (0.59) | CTSDNPSR1TSHRMGAMAMY1A | |
| SCHEMBL5000979 | 0.86 | SMN1; SMN2 (0.45) | CXCR3CTSDGUSBNPSR1TSHR | |
| SCHEMBL5000985 | 0.84 | SMN1; SMN2 (0.53) | CXCR3CTSDNPSR1TSHRNPC1 | |
| SCHEMBL1802857 | 0.78 | CXCR3 (0.57) | CXCR3NOD1CTSDGUSBNPSR1 | |
| SCHEMBL1385523 | 0.71 | KDM4E (0.71) | CTSDGUSBTSHRALDH1A1LMNA | |
| SCHEMBL6709339 | 0.69 | MAPT (0.61) | CXCR3CTSDGUSBNPC1MGAM | |
| SCHEMBL14470429 | 0.69 | F2R (0.61) | CXCR3NOD1CTSDGUSBNPSR1 | |
| SCHEMBL1801571 | 0.67 | CTSD (0.45) | CXCR3NOD1CTSDGUSBNPSR1 | |
| SCHEMBL5037413 | 0.66 | KDM4E (0.62) | TSHRALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1803118 | 0.65 | MAPT (0.59) | CTSDNPSR1TSHRMGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287681-A1 | Substituted Benzimidazoles and their Use for Inducing Apoptosis | EBERLE MARTIN | 2008-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287681-A1 | Substituted Benzimidazoles and their Use for Inducing Apoptosis | BAX, BCL2, BAD | CXCR3 1753/4885NOD1 307/4885CTSD 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.