Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 6/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALPP | P05187 | 1/20 | 0.41 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4996791 | 0.86 | CXCR3 (0.57) | SMN1; SMN2NPSR1CTSDCXCR3CYP2C9 | |
| SCHEMBL1818686 | 0.83 | MAPT (0.59) | SMN1; SMN2NPSR1CTSDTDP1LMNA | |
| SCHEMBL5000985 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPSR1F2RCTSDCXCR3 | |
| SCHEMBL2581813 | 0.73 | KDM4E (0.68) | SMN1; SMN2MAPTTSHR | |
| SCHEMBL1801571 | 0.70 | CTSD (0.45) | SMN1; SMN2NPSR1F2RCTSDCXCR3 | |
| SCHEMBL1802357 | 0.68 | F2R (0.41) | SMN1; SMN2NPSR1F2RCTSDCXCR3 | |
| SCHEMBL1800064 | 0.68 | CTSD (0.46) | SMN1; SMN2NPSR1F2RCTSDCXCR3 | |
| SCHEMBL11890510 | 0.68 | KDM4E (0.52) | SMN1; SMN2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL14470429 | 0.66 | F2R (0.61) | SMN1; SMN2NPSR1F2RCTSDCXCR3 | |
| SCHEMBL1802857 | 0.65 | CXCR3 (0.57) | SMN1; SMN2NPSR1CTSDCXCR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287681-A1 | Substituted Benzimidazoles and their Use for Inducing Apoptosis | EBERLE MARTIN | 2008-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287681-A1 | Substituted Benzimidazoles and their Use for Inducing Apoptosis | BAX, BCL2, BAD | SMN1; SMN2 2693/4885NPSR1 4369/4885F2R 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.