SCHEMBL5010291

SCHEMBL5010291

[c]1ccc(-c2ccccc2)c2c1C1CCCCC21

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PARP1 P09874 1/20 0.34
S1PR1 P21453 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4706494 0.83 CHRNB2 (0.35) CHRNB2CHRNA4
SCHEMBL5135076 0.68 ALDH1A1 (0.39) GAAMEN1KMT2AALDH1A1LMNA
SCHEMBL8058587 0.66 ALDH1A1 (0.37) GAAMEN1KMT2AALDH1A1LMNA
SCHEMBL23294 0.65 CHRNB2 (0.32) CHRNB2CHRNA4
SCHEMBL3312444 0.64 CYP19A1 (0.32) CHRNB2CHRNA4
SCHEMBL2085259 0.61 ADORA3 (0.38) GAAMEN1KMT2AALDH1A1LMNA
SCHEMBL999508 0.60 LMNA (0.34) ALDH1A1LMNA
Biphenyl SCHEMBL27543008 0.59 ALDH1A1 (0.47) MEN1KMT2AALDH1A1LMNA
SCHEMBL16817775 0.58 MAPT (0.41) GAAMEN1KMT2AALDH1A1LMNA
SCHEMBL3308914 0.58 PRCP (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450033-B2 Electrography; facsimiles, printers, copiers; polyurethanes RICOH COMPANY, LTD. (JP) 2013-05-28 US disclosed
US-20080138728-A1 LATENT ELECTROSTATIC IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2008-06-12 US disclosed