SCHEMBL5019508

SCHEMBL5019508

OCc1ccc(-c2ccc(-c3nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
ADORA3 P0DMS8 2/20 0.38
ADORA2A P29274 2/20 0.38
ADORA1 P30542 2/20 0.38
KIF11 P52732 1/20 0.37
MAP2K4 P45985 1/20 0.35
PIK3CA P42336 4/20 0.34
S1PR1 P21453 4/20 0.34
PIK3CG P48736 3/20 0.34
MTOR P42345 3/20 0.34
S1PR3 Q99500 1/20 0.34
PIK3CD O00329 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
NOTUM Q6P988 1/20 0.33
RIPK1 Q13546 1/20 0.33
HDAC2 Q92769 1/20 0.33
PDE7A Q13946 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL765590 0.98 ADORA3 (0.38) MKNK1MKNK2ADORA3ADORA2AADORA1
SCHEMBL11973820 0.89 HDAC2 (0.41) MKNK1MKNK2ADORA3ADORA2AADORA1
SCHEMBL8412982 0.82 NPC1 (0.38) ADORA3ADORA2AADORA1
SCHEMBL3343534 0.82 TP53 (0.42) S1PR1
SCHEMBL2760438 0.80 IDO1 (0.39) PDE7APDE7B
SCHEMBL2832962 0.80 TP53 (0.43) S1PR1
SCHEMBL4147404 0.79 MEN1 (0.46) KIF11
SCHEMBL14138137 0.78 ABCC4 (0.49)
SCHEMBL15316343 0.78 PRKCI (0.47) ADORA3ADORA2AADORA1MAP2K4PIK3CA
SCHEMBL3311317 0.77 L3MBTL1 (0.42) PDE7APDE7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287179-A1 HIGHLY SOLUBLE TRIS-(2,3-EPOXYPROPYL)-ISOCYANURATE AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL CORPORATION (JP) 2023-09-14 US disclosed
US-9428606-B2 Polyfunctional epoxy compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-08-30 US disclosed
US-20150353684-A1 HIGHLY SOLUBLE TRIS- (2, 3-EPOXYPROPYL)- ISOCYANURATE AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-10 US disclosed
US-9140989-B2 Photosensitive organic particles NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-09-22 US disclosed
US-8778597-B2 Long-chain alkylene-containing curable epoxy resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-07-15 US disclosed
US-8765835-B2 Epdxy resin composition having monocyclic aliphatic hydrocarbon ring NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-07-01 US disclosed
US-8652755-B2 Positive photosensitive resin composition and lyophobic film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
US-20140045119-A1 PHOTOSENSITIVE ORGANIC PARTICLES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-02-13 US disclosed
US-20130274433-A1 POLYFUNCTIONAL EPOXY COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-10-17 US disclosed
US-20130177849-A1 EPOXY RESIN COMPOSITION HAVING MONOCYCLIC ALIPHATIC HYDROCARBON RING NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-07-11 US disclosed
US-20120295199-A1 LONG-CHAIN ALKYLENE-CONTAINING CURABLE EPOXY RESIN COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-11-22 US disclosed
US-8168371-B2 Positive photosensitive resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-05-01 US disclosed
US-20100028805-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287179-A1 HIGHLY SOLUBLE TRIS-(2,3-EPOXYPROPYL)-ISOCYANURATE AND METHOD FOR PRODUCING SAME TTPA, USP1, USP2 MKNK1 1031/4885MKNK2 814/4885ADORA3 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.