Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269258 | 0.86 | CYP19A1 (0.54) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL27985237 | 0.86 | CYP3A4 (0.41) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| SCHEMBL30741761 | 0.84 | HPGDS (0.50) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| SCHEMBL28417084 | 0.84 | HPGDS (0.50) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| SCHEMBL15473178 | 0.83 | HTT (0.41) | CYP19A1KDM4CMAPTTP53 | |
| SCHEMBL28422539 | 0.82 | HPGDS (0.49) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| SCHEMBL9598245 | 0.82 | CYP3A4 (0.51) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| SCHEMBL28417071 | 0.82 | HPGDS (0.49) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| SCHEMBL28074771 | 0.82 | HPGDS (0.49) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 | |
| SCHEMBL1187114 | 0.82 | KDM4E (0.50) | HPGDSCYP3A4CYP2D6CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400229-B1 | 18/19F-LABELLED COMPOUNDS WHICH TARGET THE PROSTATE SPECIFIC MEMBRANE ANTIGEN | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2024-03-06 | — | — | EP | disclosed |
| US-11760728-B2 | Tead inhibitors and uses thereof | Ikena Oncology, Inc. (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3743430-B1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20230118205-A1 | NOVEL COMPOUNDS (IMMUNORHELINS) | ISR IMMUNE SYSTEM REGULATION HOLDING AB PUBL (SE) | 2023-04-20 | — | — | US | disclosed |
| US-11564969-B2 | Immunorhelin compounds for intracellular infections | ISR Immune System Regulation Holding AB (publ) (SE) | 2023-01-31 | — | — | US | disclosed |
| WO-2022187518-A1 | SUBSTITUTED 4-PIPERIDINYL-IMIDAZO[4,5-B]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Ikena Oncology, Inc. (US) | 2022-09-09 | — | — | WO | disclosed |
| US-11434258-B2 | Compounds (immunorhelins) | ISR Immune System Regulation Holding AB (SE) | 2022-09-06 | — | — | US | disclosed |
| WO-2020243415-A2 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2020-12-03 | — | — | WO | disclosed |
| US-10736932-B2 | Small molecule Ras inhibitors | OHIO STATE INNOVATION FOUNDATION (US) | 2020-08-11 | — | — | US | disclosed |
| US-20170304383-A1 | SMALL MOLECULE RAS INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2017-10-26 | — | — | US | disclosed |
| CN-104016925-A | Method for synthesizing 4-alkylimidazole-2-carboxylic acid I | UNIV ZUNYI MEDICAL | 2014-09-03 | — | — | CN | disclosed |
| US-8716492-B2 | Five-membered heterocycles useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-06 | — | — | US | disclosed |
| US-8551956-B2 | Compositions containing peptides with non-natural amino acids and methods of use | AVON PRODUCTS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-8551956-B2 | Compositions containing peptides with non-natural amino acids and methods of use | AVON PRODUCTS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20090082252-A1 | Compositions Containing Peptides with Non-Natural Amino Acids and Methods of Use | AVON PRODUCTS INC. | 2009-03-26 | — | — | US | disclosed |
| US-20090082252-A1 | Compositions Containing Peptides with Non-Natural Amino Acids and Methods of Use | AVON PRODUCTS INC. | 2009-03-26 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| WO-2007100874-A2 | COMPOSITIONS CONTAINING PEPTIDES WITH NON-NATURAL AMINO ACIDS AND METHODS OF USE | AVON PRODUCTS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230118205-A1 | NOVEL COMPOUNDS (IMMUNORHELINS) | GNRHR, FSHR, LHCGR | HPGDS 574/4885CYP3A4 4720/4885CYP2D6 4519/4885 |
| US-10736932-B2 | Small molecule Ras inhibitors | KRAS, NRAS, HRAS | HPGDS 721/4885CYP3A4 4177/4885CYP2D6 2378/4885 |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | HPGDS 827/4885CYP3A4 3002/4885CYP2D6 2747/4885 |
| US-20170304383-A1 | SMALL MOLECULE RAS INHIBITORS | KRAS, NRAS, HRAS | HPGDS 721/4885CYP3A4 4177/4885CYP2D6 2378/4885 |
| US-11564969-B2 | Immunorhelin compounds for intracellular infections | GNRHR, GHRHR, FSHR | HPGDS 688/4885CYP3A4 4792/4885CYP2D6 4718/4885 |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | HPGDS 4758/4885CYP3A4 1584/4885CYP2D6 427/4885 |
| US-11760728-B2 | Tead inhibitors and uses thereof | TEAD2, TEAD3, TEAD4 | HPGDS 1259/4885CYP3A4 858/4885CYP2D6 1755/4885 |
| US-20090082252-A1 | Compositions Containing Peptides with Non-Natural Amino Acids and Methods of Use | CUTA, NGLY1, LNPEP | HPGDS 2356/4885CYP3A4 4882/4885CYP2D6 4775/4885 |
| US-11434258-B2 | Compounds (immunorhelins) | GNRHR, FSHR, LHCGR | HPGDS 479/4885CYP3A4 4460/4885CYP2D6 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.