SCHEMBL502585

SCHEMBL502585

O=C(OC1O[C@H](CO)[C@@H](O)[C@H]1O)c1cccnc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.46
▸ LGALS9 O00182 1/20 0.45
▸ LGALS1 P09382 1/20 0.45
▸ LGALS3 P17931 1/20 0.45
▸ LGALS7; LGALS7B P47929 1/20 0.45
▸ MAOB P27338 1/20 0.44
▸ MAPT P10636 1/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ SLC28A3 Q9HAS3 2/20 0.43
▸ MAPK1 P28482 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25333021 1.00 ALDH1A1 (0.46) ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL29993128 1.00 ALDH1A1 (0.46) ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL21828727 1.00 ALDH1A1 (0.46) ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL25387949 1.00 ALDH1A1 (0.46) ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B
Niacinamide SCHEMBL28136690 0.85 F7 (0.51) ALDH1A1MAOBSLC28A3
Niacinamide SCHEMBL17315028 0.84 F7 (0.50) ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL19717962 0.84 LGALS9 (0.46) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL6570199 0.84 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL7141014 0.84 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL6570202 0.84 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11865127-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor TECTON GROUP, LLC (US) 2024-01-09 — — US claimed
US-20220133755-A1 COMPOSITION COMPRISING KETONE BODY AND NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATOR AND METHYL DONOR TECTON BG, INC. 2022-05-05 — — US claimed
US-11202790-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor TECTON GROUP, LLC (US) 2021-12-21 — — US claimed
CN-113727987-A Use of nicotinamide riboside, nicotinic acid riboside, reduced nicotinoyl riboside compound and nicotinoyl riboside compound derivative in preparation of articles 可劳迈戴斯有限公司 2021-11-30 — — CN claimed
US-10927101-B2 Neopetrosides A and B, and synthesis method thereof INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2021-02-23 — — US claimed
US-20210030774-A1 COMPOSITION COMPRISING KETONE BODY AND NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATOR AND METHYL DONOR TECTON BG, INC. 2021-02-04 — — US claimed
US-10688115-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor TECTON GROUP, LLC (US) 2020-06-23 — — US claimed
US-10456411-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor TECTON GROUP, LLC (US) 2019-10-29 — — US claimed
US-20190290666-A1 COMPOSITION COMPRISING KETONE BODY AND NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATOR AND METHYL DONOR TECTON BG, INC. 2019-09-26 — — US claimed
US-10376528-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor TECTON GROUP, LLC (US) 2019-08-13 — — US claimed
US-20190218206-A1 NEOPETROSIDES A AND B, AND SYNTHESIS METHOD THEREOF INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2019-07-18 — — US claimed
US-20180256612-A1 Composition Comprising Ketone Body and Nicotinamide Adenine Dinucleotide Modulator and Methyl Donor THORNE RESEARCH, INC. (US) 2018-09-13 — — US claimed
US-20260062436-A1 METHODS OF PREPARING REDUCED NICOTINAMIDE RIBOSIDE AND DERIVATIVES THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2026-03-05 — — US disclosed
EP-4472948-A4 NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF NEW FRONTIER BIO INC (US) 2026-01-21 — — EP disclosed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed
EP-3322419-B1 SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES UNIV CORNELL (US) 2025-09-03 — — EP disclosed
EP-1468698-A2 HUMAN QUINONE REDUCTASE 2 CONJUGATES FOR ADEPT AND GDEPT ENZACTA R & D LIMITED (GB) 2004-10-20 — — EP disclosed
US-20030086933-A1 Therapeutic systems ENZACTA R & D LIMITED 2003-05-08 — — US disclosed
EP-0988059-A2 HUMAN QUINONE REDUCTASE 2 CONJUGATES FOR ADEPT AND GDEPT ENZACTA R & D LIMITED (GB) 2000-03-29 — — EP disclosed
WO-1998057662-A2 THERAPEUTIC SYSTEMS ENZACTA R & D LIMITED (GB) 1998-12-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11202790-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-10456411-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-20260062436-A1 METHODS OF PREPARING REDUCED NICOTINAMIDE RIBOSIDE AND DERIVATIVES THEREOF NNT, SIRT1, NAMPT ALDH1A1 627/4885LGALS9 3888/4885LGALS1 3850/4885
US-20180256612-A1 Composition Comprising Ketone Body and Nicotinamide Adenine Dinucleotide Modulator and Methyl Donor NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-20210030774-A1 COMPOSITION COMPRISING KETONE BODY AND NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATOR AND METHYL DONOR NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-10688115-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-10376528-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-20220133755-A1 COMPOSITION COMPRISING KETONE BODY AND NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATOR AND METHYL DONOR NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-11865127-B2 Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-20190290666-A1 COMPOSITION COMPRISING KETONE BODY AND NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATOR AND METHYL DONOR NNMT, NNT, NADK ALDH1A1 814/4885LGALS9 3708/4885LGALS1 3074/4885
US-20190218206-A1 NEOPETROSIDES A AND B, AND SYNTHESIS METHOD THEREOF NPPA, NME4, PINK1 ALDH1A1 3266/4885LGALS9 4061/4885LGALS1 3853/4885
US-20030086933-A1 Therapeutic systems NQO2, NQO1, NAPRT ALDH1A1 1498/4885LGALS9 4826/4885LGALS1 4880/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 ALDH1A1 1153/4885LGALS9 904/4885LGALS1 693/4885
US-10927101-B2 Neopetrosides A and B, and synthesis method thereof NPPA, NME4, PINK1 ALDH1A1 3266/4885LGALS9 4061/4885LGALS1 3853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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