SCHEMBL5026697

SCHEMBL5026697

COc1cccc2c3ccccc3n(C)c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.59
FTO Q9C0B1 1/20 0.59
CYP19A1 P11511 1/20 0.54
NQO2 P16083 1/20 0.54
KDM4E B2RXH2 4/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
HTT P42858 2/20 0.54
HSD17B10 Q99714 2/20 0.54
GLA P06280 1/20 0.54
GAA P10253 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
ATM Q13315 1/20 0.54
GPR3 P46089 1/20 0.54
MAPT P10636 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HSP90AA1 P07900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28691180 0.86 KDM4E (0.63) CYP19A1NQO2KDM4EALDH1A1HPGD
SCHEMBL20650932 0.86 CYP19A1 (0.62) CYP19A1NQO2KDM4EALDH1A1HPGD
SCHEMBL4373659 0.83 CYP19A1 (0.53) ALKBH5FTOCYP19A1NQO2KDM4E
SCHEMBL15466278 0.81 ALKBH5 (0.54) ALKBH5FTOKDM4EALDH1A1HPGD
SCHEMBL24311758 0.80 KDM4E (0.53) ALKBH5FTOCYP19A1NQO2KDM4E
SCHEMBL28606326 0.80 CYP19A1 (0.41) ALKBH5FTOCYP19A1NQO2KDM4E
SCHEMBL31515799 0.80 ALKBH5 (0.57) ALKBH5FTOCYP19A1NQO2KDM4E
SCHEMBL28984467 0.80 ALKBH5 (0.53) ALKBH5FTOKDM4EALDH1A1HPGD
SCHEMBL15465966 0.78 GPR3 (0.54) CYP19A1NQO2KDM4EALDH1A1HPGD
SCHEMBL3423943 0.78 GPR3 (0.71) ALKBH5FTONQO2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-11335872-B2 Organic light-emitting device KYULUX, INC. (JP) 2022-05-17 US disclosed
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-03 US disclosed
US-20210234113-A1 ORGANIC LIGHT-EMITTING DEVICE KYULUX, INC. (JP) 2021-07-29 US disclosed
US-20200259112-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2020-08-13 US disclosed
US-10510977-B2 Compound, light-emitting material, and organic light-emitting device KYULUX, INC. (JP) 2019-12-17 US disclosed
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2019-07-18 US disclosed
US-20190016704-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING DEVICE KYULUX, INC. (JP) 2019-01-17 US disclosed
US-10043978-B2 Organic semiconductor formulations FLEXTERRA, INC. (US) 2018-08-07 US disclosed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US disclosed
US-9293711-B2 Organic semiconductor formulations POLYERA CORPORATION (US) 2016-03-22 US disclosed
US-20140042369-A1 Organic Semiconductor Formulations USINVEST LLC 2014-02-13 US disclosed
US-20080146810-A1 NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS S.A. (CH) 2008-06-19 US disclosed
EP-1554262-B1 NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LTD (IN) 2007-12-05 EP disclosed
US-7238725-B2 Tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them GLENMARK PHARMACEUTICALS LTD. (IN) 2007-07-03 US disclosed
US-20060178418-A1 Novel tricyclic compounds useful for the treatment of inflammatory and allergic disorders:process for their preparation and pharmaceutical compositions containing them GLENMARK PHARMACEUTICALS LTD. (IN) 2006-08-10 US disclosed
EP-1554262-A1 NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Glenmark Pharmaceuticals Limited (IN) 2005-07-20 EP disclosed
WO-2004037805-A1 NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LTD. (US) 2004-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080146810-A1 NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LTC4S, TSLP, GPR119 ALKBH5 4786/4885FTO 4525/4885CYP19A1 248/4885
US-20190016704-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, CYBA ALKBH5 3225/4885FTO 1419/4885CYP19A1 2109/4885
US-20060178418-A1 Novel tricyclic compounds useful for the treatment of inflammatory and allergic disorders:process for their preparation and pharmaceutical compositions containing them LTC4S, TSLP, GPR119 ALKBH5 4786/4885FTO 4525/4885CYP19A1 248/4885
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, LBR, CNKSR1 ALKBH5 2639/4885FTO 1305/4885CYP19A1 2133/4885
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT SLC43A1, SLC7A5, SLC39A3 ALKBH5 4113/4885FTO 1823/4885CYP19A1 1813/4885
US-10510977-B2 Compound, light-emitting material, and organic light-emitting device CRY1, CRY2, CYBA ALKBH5 3225/4885FTO 1419/4885CYP19A1 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.