Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | BCL2 | P10415 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837838 | 0.93 | GSTP1 (0.44) | GSTP1GSTM2KLK5CYP11B1CYP11B2 | |
| SCHEMBL9837834 | 0.93 | GSTP1 (0.44) | GSTP1GSTM2KLK5CYP11B1CYP11B2 | |
| Histidine SCHEMBL18301538 | 0.88 | GSTP1 (0.37) | GSTP1GSTM2KLK5BCL2PPARG | |
| Histidine SCHEMBL18301539 | 0.88 | GSTP1 (0.37) | GSTP1GSTM2KLK5BCL2PPARG | |
| SCHEMBL9837440 | 0.87 | ITGA4 (0.42) | KLK5CYP11B1CYP11B2ACEFNTA | |
| SCHEMBL9837445 | 0.87 | ITGA4 (0.42) | KLK5CYP11B1CYP11B2ACEFNTA | |
| SCHEMBL28058939 | 0.83 | ALDH1A1 (0.48) | CYP11B1CYP11B2ACEFNTAFNTB | |
| SCHEMBL16245923 | 0.83 | ALDH1A1 (0.48) | CYP11B1CYP11B2ACEFNTAFNTB | |
| SCHEMBL8254417 | 0.82 | CYP11B1 (0.53) | KLK5CYP11B1CYP11B2PPARGPPARA | |
| SCHEMBL16967378 | 0.76 | ACE2 (0.41) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | UNIV NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | NEW YORK UNIVERSITY | 2024-04-18 | — | — | US | disclosed |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2024-02-06 | — | — | US | disclosed |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | CORNELL UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2022-09-13 | — | — | US | disclosed |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2021-09-09 | — | — | US | disclosed |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200190155-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY | 2020-06-18 | — | — | US | disclosed |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY | 2018-06-14 | — | — | US | disclosed |
| US-8445678-B2 | 2-quinoxalinol salen compounds and uses thereof | AUBURN UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120028362-A1 | 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF | AUBURN UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | AUBURN UNIVERSITY (US) | 2009-11-19 | — | — | US | disclosed |
| EP-0589665-B1 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA CHEMICAL IND CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5401736-A | Angiotensis II antagonists | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0589665-A2 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | GSTP1 3126/4885GSTM2 1035/4885KLK5 4119/4885 |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, SMC2 | GSTP1 4598/4885GSTM2 3095/4885KLK5 3142/4885 |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, CRYZ | GSTP1 4358/4885GSTM2 2319/4885KLK5 3070/4885 |
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | NQO1, NQO2, SQOR | GSTP1 668/4885GSTM2 331/4885KLK5 1806/4885 |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | GSTP1 4358/4885GSTM2 2319/4885KLK5 3070/4885 |
| US-20120028362-A1 | 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF | NQO1, NQO2, SQOR | GSTP1 668/4885GSTM2 331/4885KLK5 1806/4885 |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | SOS2, SOS1, F2 | GSTP1 1682/4885GSTM2 270/4885KLK5 4551/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | GSTP1 2489/4885GSTM2 1067/4885KLK5 4878/4885 |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | GSTP1 3126/4885GSTM2 1035/4885KLK5 4119/4885 |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | GSTP1 3126/4885GSTM2 1035/4885KLK5 4119/4885 |
| US-20200190155-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | GSTP1 3126/4885GSTM2 1035/4885KLK5 4119/4885 |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | GSTP1 4358/4885GSTM2 2319/4885KLK5 3070/4885 |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | GSTP1 3229/4885GSTM2 1169/4885KLK5 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.