SCHEMBL5034680

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5034854	0.90	HPGD (0.45)	MAPTHTTNPSR1KMT2AMEN1
	SCHEMBL5041390	0.88	KMT2A (0.42)	MAPTHTTNPSR1KMT2AMEN1
	SCHEMBL5032635	0.86	FLT1 (0.40)	MAPTHTTNPSR1KMT2AMEN1
	SCHEMBL5035146	0.86	FLT1 (0.39)	MAPTHTTNPSR1KMT2AMEN1
	SCHEMBL5035133	0.82	HPGD (0.47)	MAPTHTTNPSR1KMT2AMEN1
	SCHEMBL5032622	0.82	FLT1 (0.40)	MAPTKMT2AMEN1CYP3A4TSHR
	SCHEMBL5032527	0.82	ALDH1A1 (0.46)	MAPTKMT2AMEN1CYP3A4TSHR
	SCHEMBL5035872	0.81	LMNA (0.48)	MAPTNPSR1CYP3A4TSHRHPGD
	SCHEMBL5034722	0.81	CYP3A4 (0.44)	MAPTHTTNPSR1CYP3A4TSHR
	SCHEMBL5032525	0.81	CRHR1 (0.39)	MAPTHTTNPSR1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.