SCHEMBL503577

SCHEMBL503577

Cc1cc(C)c(Nc2ccccc2)c(C)c1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 18/20 0.72
HPGD P15428 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15649491 0.88 RAPGEF4 (0.68) RAPGEF4
SCHEMBL17383515 0.88 RAPGEF4 (0.57) RAPGEF4HPGDNPSR1
SCHEMBL9312386 0.86 RAPGEF4 (0.54) RAPGEF4HPGDNPSR1
SCHEMBL15188815 0.84 RAPGEF4 (1.00) RAPGEF4
SCHEMBL18734414 0.83 RAPGEF4 (0.72) RAPGEF4NPSR1
SCHEMBL31426811 0.83 RAPGEF4 (0.59) RAPGEF4HPGDNPSR1
SCHEMBL801391 0.82 RAPGEF4 (0.79) RAPGEF4
Trifluoromethanesulfonic Acid SCHEMBL16588848 0.82 RAPGEF4 (0.54) RAPGEF4
SCHEMBL8014673 0.81 ALDH1A1 (0.61) RAPGEF4HPGDNPSR1
SCHEMBL31364548 0.81 RAPGEF4 (0.70) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327267-B Low-viscosity aniline polyether polyol and preparation method and application thereof SHANDONG INOV NEW MATERIAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-118684623-A Complexing agent and preparation method and application thereof 中国第一汽车股份有限公司 2024-09-24 CN claimed
WO-2024061102-A1 COMPOSITE MATERIAL, COMPOSITION AND LIGHT-EMITTING DIODE TCL科技集团股份有限公司 2024-03-28 WO claimed
EP-3830233-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS Milliken & Company (US) 2021-06-09 EP claimed
WO-2020023897-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY (US) 2020-01-30 WO claimed
CN-108011046-A A kind of method of perovskite surface in situ method growth perovskite nano wire and a kind of perovskite solar cell 浙江理工大学 2018-05-08 CN claimed
EP-2379473-B1 DIACENAPHTHO[1,2-B:1',2'-K]CHRYSENE DERIVATIVE CANON KK (JP) 2017-02-22 EP claimed
CN-104979474-A Laminated solar battery based on perovskite battery and HIT battery and manufacturing method INST SEMICONDUCTORS CAS 2015-10-14 CN claimed
CN-117327267-B Low-viscosity aniline polyether polyol and preparation method and application thereof SHANDONG INOV NEW MATERIAL Co.,Ltd. (CN) 2026-05-26 CN disclosed
US-20250366368-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-11-27 US disclosed
US-12439821-B2 Light emitting device and fused polycyclic compound for light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2025-10-07 US disclosed
US-20250197643-A1 PHOTOSENSITIVE COMPOSITION REACTIVE DYE AND PHOTO-CURABLE COMPOSITION WITH REACTIVE DYE DUK SAN NEOLUX CO., LTD (KR) 2025-06-19 US disclosed
CN-112940024-B Organic electroluminescent device and organometallic compound for organic electroluminescent device 三星显示有限公司 2025-03-11 CN disclosed
CN-112194672-B Organic electroluminescent device and condensed polycyclic compound 三星显示有限公司 2025-02-21 CN disclosed
US-20060121312-A1 Fluorene compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2006-06-08 US disclosed
US-20060113528-A1 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2006-06-01 US disclosed
US-20060115678-A1 Aminoanthryl derivative-substituted pyrene compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2006-06-01 US disclosed
US-20050099115-A1 Substituted anthryl derivative and electoluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2005-05-12 US disclosed
US-20040263067-A1 Anthryl derivative group substituted compound, and organic luminescent device making use of same CANON KABUSHIKI KAISHA (JP) 2004-12-30 US disclosed
US-20040265632-A1 Organic electroluminescent device CANON KABUSHIKI KAISHA (JP) 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12439821-B2 Light emitting device and fused polycyclic compound for light emitting device LEF1, NFE2L2, CACNA2D1 RAPGEF4 3126/4885HPGD 3529/4885NPSR1 2509/4885
US-20060121312-A1 Fluorene compound and organic light-emitting device LEF1, AFF1, FLI1 RAPGEF4 2004/4885HPGD 3601/4885NPSR1 3491/4885
US-20250366368-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR LIGHT EMITTING DEVICE LEF1, NFE2L2, CACNA2D1 RAPGEF4 3126/4885HPGD 3529/4885NPSR1 2509/4885
US-20050099115-A1 Substituted anthryl derivative and electoluminescence device using the same ALAD, ERAL1, LAGE3 RAPGEF4 1886/4885HPGD 483/4885NPSR1 4540/4885
US-20060115678-A1 Aminoanthryl derivative-substituted pyrene compound and organic light-emitting device ALAD, PAH, PPOX RAPGEF4 3789/4885HPGD 1086/4885NPSR1 4540/4885
US-20040263067-A1 Anthryl derivative group substituted compound, and organic luminescent device making use of same ALAD, AAAS, NLRP1 RAPGEF4 809/4885HPGD 515/4885NPSR1 4803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.