Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12576029 | 0.86 | CYP2A6 (0.55) | CYP2A6ALOX15HTTCYP11B1CYP11B2 | |
| SCHEMBL14392676 | 0.85 | CYP2A6 (0.61) | CYP2A6ALOX15HTTCYP11B1CYP11B2 | |
| SCHEMBL16675071 | 0.84 | CYP2A6 (0.53) | CYP2A6CYP11B1CYP11B2GABRA1GABRG2 | |
| SCHEMBL18253593 | 0.84 | CYP11B2 (0.48) | CYP2A6ALOX15HTTALDH1A1CYP11B2 | |
| SCHEMBL5851006 | 0.83 | XDH (0.47) | CYP2A6ALOX15HTTCYP11B1CYP11B2 | |
| SCHEMBL722248 | 0.83 | ATM (0.62) | CYP2A6ATMALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL21692173 | 0.83 | ATM (0.62) | CYP2A6ATMALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL30335566 | 0.83 | CYP2A6 (0.62) | CYP2A6ALOX15HTTALDH1A1CYP11B1 | |
| SCHEMBL4270686 | 0.83 | CYP2A6 (0.62) | CYP2A6ALOX15HTTALDH1A1CYP11B1 | |
| SCHEMBL5115735 | 0.82 | CYP2A6 (0.60) | CYP2A6HTTALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PEPTIDREAM INC (JP) | 2026-01-15 | — | — | US | disclosed |
| US-12509424-B2 | Compound and composition as PDGF receptor kinase inhibitor | NIPPON SHINYAKU CO., LTD. (JP) | 2025-12-30 | — | — | US | disclosed |
| US-12486232-B2 | Method for preparing meta-functionalized pyridine compound | NANKAI UNIVERSITY (CN) | 2025-12-02 | — | — | US | disclosed |
| US-20250257035-A1 | 1,4-Substituted Piperidine Derivatives | CEPHALON LLC | 2025-08-14 | — | — | US | disclosed |
| US-20250179021-A1 | Method For Preparing Meta-Functionalized Pyridine Compound | CNBM RESEARCH INSTITUTE FOR ADVANCED GLASS MATERIALS GROUP CO., LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
| US-20250160203-A1 | Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2025-05-15 | — | — | US | disclosed |
| US-12295260-B2 | Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2025-05-06 | — | — | US | disclosed |
| EP-4534524-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PeptiDream Inc. (JP) | 2025-04-09 | — | — | EP | disclosed |
| EP-4516777-A2 | COMPOUND AND COMPOSITION AS PDGF RECEPTOR KINASE INHIBITOR | Nippon Shinyaku Co., Ltd. (JP) | 2025-03-05 | — | — | EP | disclosed |
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| EP-0970083-A1 | 7a-HETEROCYCLE-SUBSTITUTED HEXAHYDRO-1H-PYRROLIZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1999021834-A1 | HETEROARYL DIAZACYCLOALKANES AS CHOLINERGIC LIGANDS AT NICOTINIC ACETYLCHOLINE RECEPTORS | NEUROSEARCH A/S (DK) | 1999-05-06 | — | — | WO | disclosed |
| US-5861423-A | SIDE EFFECT REDUCTION; ADMINISTERING TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS; ALZHEIMER*S AND PARKINSON*S DISEASE; ATTENTION DEFICIT DISORDER, SCHIZOPHRENIA | TARGACEPT, INC., A CORPORATION OF DELAWARE | 1999-01-19 | — | — | US | disclosed |
| WO-1998054182-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 1998-12-03 | — | — | WO | disclosed |
| US-5811442-A | ADMINISTERING ARYL SUBSTITUTED OLEFINIC AMINE COMPOUND IN AN AMOUNT SUFFICIENT TO SELECTIVELY BIND TO AND AFFECT NICOTINIC CHOLINERGIC RECEPTOR SUBTYPES CONTAINING BETA2 SUBUNITS | TARGACEPT, INC. | 1998-09-22 | — | — | US | disclosed |
| WO-1998037071-A1 | PHARMACEUTICAL COMPOSITIONS INCORPORATING ARYL SUBSTITUTED OLEFINIC AMINE COMPOUNDS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1998-08-27 | — | — | WO | disclosed |
| WO-1998037082-A1 | 7a-HETEROCYCLE-SUBSTITUTED HEXAHYDRO-1H-PYRROLIZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1998-08-27 | — | — | WO | disclosed |
| US-5733912-A | NERVOUS SYSTEM DISORDERS IN NERVE CELLS | ABBOTT LABORATORIES (US) | 1998-03-31 | — | — | US | disclosed |
| US-5409920-A | 2-(3-pyridyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0479574-A2 | 2-(3-pyridyl)-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257035-A1 | 1,4-Substituted Piperidine Derivatives | FASN, CES1, CPT1A | CYP2A6 234/4885ATM 4593/4885ALOX15 116/4885 |
| US-12295260-B2 | Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device | NQO1, CYP1A1, CYBA | CYP2A6 351/4885ATM 1358/4885ALOX15 493/4885 |
| US-20250160203-A1 | Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device | NQO1, CYP1A1, CYBA | CYP2A6 351/4885ATM 1358/4885ALOX15 493/4885 |
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | NSUN3, BCAT1, SLC43A1 | CYP2A6 1570/4885ATM 4553/4885ALOX15 3301/4885 |
| US-12509424-B2 | Compound and composition as PDGF receptor kinase inhibitor | PDGFRA, PDGFRB, PDGFA | CYP2A6 3817/4885ATM 2395/4885ALOX15 1636/4885 |
| US-12486232-B2 | Method for preparing meta-functionalized pyridine compound | GAPVD1, SKP1, PDXK | CYP2A6 719/4885ATM 2685/4885ALOX15 4345/4885 |
| US-20250179021-A1 | Method For Preparing Meta-Functionalized Pyridine Compound | GAPVD1, SKP1, PDXK | CYP2A6 719/4885ATM 2685/4885ALOX15 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.