Ethyl Acetate

Ethyl Acetate

SCHEMBL505274

CCOC(C)=O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 known ✓ P08912 2/20 0.42
CHRM1 known ✓ P11229 2/20 0.42
CHRM3 known ✓ P20309 2/20 0.42
CHRM2 known ✓ P08172 1/20 0.42
CHRM4 known ✓ P08173 1/20 0.42
HTR1A known ✓ P08908 1/20 0.42
ALDH1A1 P00352 6/20 0.93
LMNA P02545 1/20 0.93
HSD17B10 Q99714 1/20 0.93
TSHR P16473 2/20 0.55
GAA P10253 2/20 0.50
ALOX15 P16050 1/20 0.50
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
SOAT1 P35610 1/20 0.50
TRPA1 O75762 1/20 0.46
GLO1 Q04760 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL18498857 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL16267234 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL192603 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL508898 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL525361 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL5036694 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL9731700 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL18237169 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL1163855 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL1150646 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164497-A Synthesis method of pyrrole-2-ketone compound 华南理工大学 2023-12-05 CN claimed
CN-111484437-B Method for introducing tertiary isopentenyl group to C3 position of indole 中国科学院大连化学物理研究所 2022-06-07 CN claimed
CN-111484436-B Method for introducing isopentene group into C3 position of indole 中国科学院大连化学物理研究所 2022-06-07 CN claimed
CN-111943938-A Synthetic method of A2A adenosine receptor antagonist 上海再极医药科技有限公司 2020-11-17 CN claimed
CN-111484437-A Method for introducing tertiary isopentenyl group to C3 position of indole 中国科学院大连化学物理研究所 2020-08-04 CN claimed
CN-111484436-A Method for introducing isopentenyl group to C3 position of indole 中国科学院大连化学物理研究所 2020-08-04 CN claimed
US-20240239788-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2024-07-18 US disclosed
US-20240238304-A1 Small Molecule Degraders of DOT1L and Uses Thereof NORTHWESTERN UNIVERSITY 2024-07-18 US disclosed
US-20240238430-A1 ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2024-07-18 US disclosed
US-20240239778-A1 GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-07-18 US disclosed
US-20240238423-A9 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS Treeline Biosciences, Inc. 2024-07-18 US disclosed
US-20240239777-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-07-18 US disclosed
CN-118344370-A Isoindolinone and indazole compounds for EGFR degradation C4医药公司 2024-07-16 CN disclosed
US-7318950-B2 Chiral compounds II MERCK GMBH (DE) 2008-01-15 US disclosed
CN-101037413-A Pyrezole compound or medicinal salt and medicine composition SUN PIAOYANG (CN) 2007-09-19 CN disclosed
US-20030178601-A1 Chiral compounds II MERCK PATENT GMBH (DE) 2003-09-25 US disclosed
EP-0690866-A4 COPPER CATALYZED COUPLING REACTIONS UNIV CALIFORNIA (US) 1996-06-12 EP disclosed
EP-0690866-A1 COPPER CATALYZED COUPLING REACTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-01-10 EP disclosed
US-5405981-A Copper catalyzed coupling reactions THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-04-11 US disclosed
WO-1994022877-A1 COPPER CATALYZED COUPLING REACTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238430-A1 ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF CA14, CA12, CA13 CHRM5 3628/4885CHRM1 3913/4885CHRM3 3081/4885
US-20240239778-A1 GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF ACBD3, NR3C1, GRN CHRM5 703/4885CHRM1 403/4885CHRM3 812/4885
US-20240239788-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT KRAS, NRAS, HRAS CHRM5 4884/4885CHRM1 4860/4885CHRM3 4872/4885
US-20240239777-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 CHRM5 4550/4885CHRM1 4719/4885CHRM3 4394/4885
US-20240238304-A1 Small Molecule Degraders of DOT1L and Uses Thereof DOT1L, STUB1, BAZ2B CHRM5 4802/4885CHRM1 4795/4885CHRM3 4753/4885
US-20240238423-A9 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS BCL2A1, BCL2L1, BCL3 CHRM5 4872/4885CHRM1 4745/4885CHRM3 4860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.