Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | CFTR | P13569 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895994 | 0.86 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL505249 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL31589985 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL17707765 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRLMNACA1 | |
| SCHEMBL63699 | 0.80 | TSHR (0.61) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL31038441 | 0.79 | LMNA (0.66) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL14828745 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL31634613 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL9639243 | 0.79 | TSHR (0.55) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL30631292 | 0.79 | CA1 (0.53) | ALDH1A1HSD17B10CFTRTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220046923-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | US | disclosed |
| EP-3898594-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-109071411-B | Method for producing nitrobenzene compound | 组合化学工业株式会社 | 2021-08-27 | — | — | CN | disclosed |
| CN-113195455-A | Herbicidal cinnolinium compounds | 先正达农作物保护股份公司 | 2021-07-30 | — | — | CN | disclosed |
| EP-3456705-B1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2020-12-16 | — | — | EP | disclosed |
| WO-2020127168-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| EP-3456705-A1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | Kumiai Chemical Industry Co., Ltd. (JP) | 2019-03-20 | — | — | EP | disclosed |
| CN-109071411-A | The method for manufacturing nitrobenzene compound | 组合化学工业株式会社 | 2018-12-21 | — | — | CN | disclosed |
| CN-108602812-A | It can be used as the bicycle hydroxamic acid compound of the inhibitor of mammal histone deacetylase activity | 坎塞拉有限公司 | 2018-09-28 | — | — | CN | disclosed |
| EP-3015451-B1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9006454-B2 | Dihydroorotate dehydrogenase inhibitors | MERCK SERONO S.A. (CH) | 2015-04-14 | — | — | US | disclosed |
| EP-2611774-B1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-03-18 | — | — | EP | disclosed |
| EP-2414328-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| US-20120028959-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2012-02-02 | — | — | US | disclosed |
| US-20120028959-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2012-02-02 | — | — | US | disclosed |
| WO-2010115736-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010115736-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |
| US-6187779-B1 | ADMINISTERING ANTITUMOR AGENTS TO TREAT COLON CANCER | CELL PATHWAYS, INC. | 2001-02-13 | — | — | US | disclosed |
| US-5721238-A | ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-24 | — | — | US | disclosed |
| CN-1134417-A | 2, 8-disubstituted quinazolinones | BAYER AG (DE) | 1996-10-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028959-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | DHODH, FH, DPYD | ALDH1A1 95/4885HSD17B10 199/4885CFTR 3051/4885 |
| US-20220046923-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | DDT, DERL1, CES2 | ALDH1A1 34/4885HSD17B10 141/4885CFTR 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.