Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL33523877 | 0.83 | — | — | |
| Fluoride Ion SCHEMBL29029426 | 0.83 | — | — | |
| SCHEMBL780 | 0.82 | — | — | |
| SCHEMBL29940263 | 0.82 | — | — | |
| SCHEMBL8778140 | 0.73 | — | — | |
| SCHEMBL1493171 | 0.73 | — | — | |
| Phosphine SCHEMBL63647 | 0.73 | — | — | |
| SCHEMBL20488766 | 0.73 | — | — | |
| SCHEMBL64817 | 0.73 | — | — | |
| Potassium SCHEMBL298979 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278909-B | Post-treatment method of mirabegron intermediate | 浙江华海药业股份有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114685515-A | Preparation method of tofacitinib | 上海蓝乐鸟实业有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-107827791-B | A kind of synthetic method of stable isotope labeling Thiamphenicol | 山东辉璟生物医药科技有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-106278909-A | A kind of post-processing approach of Mirabegron intermediate | 浙江华海药业股份有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-103664657-A | New preparation method for bisoprolol fumarate | UNIV SICHUAN | 2014-03-26 | — | — | CN | claimed |
| CN-101573034-B | Method for synthesizing (+) and (-) -1- (3, 4-dichlorophenyl) -3-azabicyclo [3.1.0] hexane | DOV PHARMACEUTICAL INC | 2013-01-02 | — | — | CN | claimed |
| CN-101573034-A | Method for synthesizing (+) and (-) -1- (3, 4-dichlorophenyl) -3-azabicyclo [3.1.0] hexane | DOV PHARMACEUTICAL INC (US) | 2009-11-04 | — | — | CN | claimed |
| CN-117682975-A | Preparation method of idexalone | 重庆东得医药科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117586166-A | Compound for preparing Ai Shali ketone and preparation method thereof | 重庆东得医药科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-108250046-B | Synthesis method of resveratrol | 上海巧坤化工科技有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-106278909-B | Post-treatment method of mirabegron intermediate | 浙江华海药业股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114685515-A | Preparation method of tofacitinib | 上海蓝乐鸟实业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-111004135-B | Synthesis method of (1R) -2- [ [ [2- (4-aminophenyl) ethyl ] amino ] methyl ] benzyl alcohol | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-1143960-A | Therapeutic heterocyclic compounds | WELLCOME FOUND (GB) | 1997-02-26 | — | — | CN | disclosed |
| CN-1006464-B | PROCESS FOR PREPARING NAPHTHALENE DERIVATIVES | TANABE SEIYAKU CO (JP) | 1990-01-17 | — | — | CN | disclosed |
| CN-86100090-A | The preparation method of naphthalene derivatives | — | 1986-08-20 | — | — | CN | disclosed |
| US-4159966-A | Chromatographic column packing | THE DOW CHEMICAL COMPANY (US) | 1979-07-03 | — | — | US | disclosed |
| US-4010280-A | PHENOXYALKYLAMINE DERIVATIVES AND PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-01 | — | — | US | disclosed |
| US-4009275-A | Phenoxypropylamine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |
| US-3978140-A | PROCESS FOR THE PREPARATION OF CARBINOLS | ALDRICH-BORANES, INC. (US) | 1976-08-31 | — | — | US | disclosed |