Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | CFD | P00746 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119894 | 0.93 | HDAC6 (0.66) | HDAC6HDAC2HDAC8TSHRCYP1A2 | |
| SCHEMBL26167889 | 0.90 | NR1H4 (0.69) | HDAC6HDAC2HDAC8TSHRCYP1A2 | |
| SCHEMBL11900090 | 0.89 | HDAC6 (0.85) | HDAC6HDAC2HDAC8TSHRHDAC1 | |
| SCHEMBL4925434 | 0.88 | CFD (0.62) | HDAC6HDAC2HDAC8TSHRCYP1A2 | |
| SCHEMBL27600905 | 0.88 | HPGD (0.78) | HDAC6HDAC1HPGDLMNARAB9A | |
| SCHEMBL4928443 | 0.87 | CFD (0.74) | HDAC6HDAC2HDAC8TSHRCYP1A2 | |
| SCHEMBL13133467 | 0.87 | HDAC6 (0.66) | HDAC6HDAC2HDAC8TSHRHDAC1 | |
| Hydrochloric Acid SCHEMBL2210739 | 0.85 | HDAC6 (0.64) | HDAC6HDAC2HDAC8TSHRHDAC1 | |
| SCHEMBL457082 | 0.85 | HDAC6 (0.79) | HDAC6HDAC2HDAC8HDAC1HPGD | |
| SCHEMBL8269164 | 0.85 | EPHX2 (0.69) | HDAC6HDAC8CYP1A2CYP2C19HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753524-B2 | Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions | PLASTIPAK PACKAGING, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-20220073700-A1 | OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS | WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT | 2022-03-10 | — | — | US | disclosed |
| US-11066536-B2 | Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions | PLASTIPAK PACKAGING, INC. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200172702-A1 | OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS | WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT | 2020-06-04 | — | — | US | disclosed |
| US-10351692-B2 | Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions | PLASTIPAK PACKAGING, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| WO-2016061503-A1 | OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS | PLASTIPAK PACKAGING, INC. (US) | 2016-04-21 | — | — | WO | disclosed |
| US-20160108207-A1 | OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS | PLASTIPAK PACKAGING, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| EP-1720836-B1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2014-04-16 | — | — | EP | disclosed |
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | disclosed |
| EP-2479168-A1 | 6-Substituted 2,3,4,5-Tetrahydro-1H-Benzo [d]Azepines as 5-HT2C Receptor Agonists | ELI LILLY AND COMPANY (US) | 2012-07-25 | — | — | EP | disclosed |
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | ELI LILLY AND COMPANY (US) | 2012-02-02 | — | — | US | disclosed |
| US-8022062-B2 | 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists | ELI LILLY AND COMPANY (US) | 2011-09-20 | — | — | US | disclosed |
| US-7759347-B2 | 2-benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| US-20090124628-A1 | 2-benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-14 | — | — | US | disclosed |
| US-20090099155-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ARRAY BIOPHARMA, INC. | 2009-04-16 | — | — | US | disclosed |
| EP-1761536-B1 | NOVEL 2-BENZYLAMINODIHYDROPTERIDINONES, METHOD FOR PRODUCING THEM AND USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INT (DE) | 2007-12-26 | — | — | EP | disclosed |
| EP-1761536-A1 | NOVEL 2-BENZYLAMINODIHYDROPTERIDINONES, METHOD FOR PRODUCING THEM AND USE THEREOF AS DRUGS | Boehringer Ingelheim International GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| US-20060004014-A1 | 2-Benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-05 | — | — | US | disclosed |
| WO-2005123736-A1 | NOVEL 2-BENZYLAMINODIHYDROPTERIDINONES, METHOD FOR PRODUCING THEM AND USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099155-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | HTR2C, HTR5A, HTR4 | HDAC6 1861/4885HDAC2 1169/4885HDAC8 1964/4885 |
| US-20220073700-A1 | OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS | PRDX5, LPO, CAT | HDAC6 2855/4885HDAC2 4544/4885HDAC8 4675/4885 |
| US-20160108207-A1 | OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS | PRDX5, LPO, CAT | HDAC6 2855/4885HDAC2 4544/4885HDAC8 4675/4885 |
| US-11753524-B2 | Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions | PRDX5, LPO, CAT | HDAC6 2855/4885HDAC2 4544/4885HDAC8 4675/4885 |
| US-10351692-B2 | Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions | PRDX5, LPO, CAT | HDAC6 2855/4885HDAC2 4544/4885HDAC8 4675/4885 |
| US-20090124628-A1 | 2-benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments | QDPR, DHPS, CYP51A1 | HDAC6 4611/4885HDAC2 4389/4885HDAC8 4842/4885 |
| US-20200172702-A1 | OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS | PRDX5, LPO, CAT | HDAC6 2855/4885HDAC2 4544/4885HDAC8 4675/4885 |
| US-20060004014-A1 | 2-Benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments | QDPR, DHPS, CYP51A1 | HDAC6 4611/4885HDAC2 4389/4885HDAC8 4842/4885 |
| US-11066536-B2 | Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions | PRDX5, LPO, CAT | HDAC6 2855/4885HDAC2 4544/4885HDAC8 4675/4885 |
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | HTR2C, HTR4, HTR1A | HDAC6 2510/4885HDAC2 3135/4885HDAC8 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.