SCHEMBL5075646

SCHEMBL5075646

Cc1ccccc1S(=O)(=O)I

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ACHE P22303 1/20 0.43
RAPGEF4 Q8WZA2 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD11B1 P28845 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
EDNRA P25101 1/20 0.40
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR2 Q92731 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6113033 0.81 KMT2A (0.45) TSHRACHEALDH1A1KDM4EEDNRA
SCHEMBL9745390 0.81 GAA (0.43) TSHRALDH1A1TDP1MEN1GAA
SCHEMBL4533183 0.79 TSHR (0.47) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL29468592 0.79 ALDH1A1 (0.55) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL475089 0.79 ALDH1A1 (0.55) TSHRACHERAPGEF4ALDH1A1KDM4E
O-Xylene SCHEMBL27875104 0.78 TSHR (0.62) TSHRACHEALDH1A1TDP1KEAP1
SCHEMBL6927887 0.78 EDNRA (0.54) ALDH1A1KDM4EL3MBTL1TP53TDP1
SCHEMBL12307 0.77 L3MBTL1 (0.50) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL79052 0.77 TSHR (0.45) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL28278788 0.77 L3MBTL1 (0.50) TSHRACHERAPGEF4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3708561-B1 POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREOF HANMI FINE CHEMICAL CO LTD (KR) 2024-05-08 EP disclosed
EP-3924396-B1 REVERSE IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-19 EP disclosed
EP-3924392-B1 IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-22 EP disclosed
EP-3924396-A1 REVERSE IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM Dow Global Technologies LLC (US) 2021-12-22 EP disclosed
US-11168180-B2 Polyethylene glycol derivative and preparation method thereof HANMI FINE CHEMICAL CO., LTD. 2021-11-09 US disclosed
EP-3708561-A2 POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREOF Hanmi Fine Chemical Co., Ltd. (KR) 2020-09-16 EP disclosed
WO-2020167600-A1 REVERSE IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2020-08-20 WO disclosed
US-20200231749-A1 Polyethylene Glycol Derivative And Preparation Method Thereof HANMI FINE CHEMICAL CO., LTD. (KR) 2020-07-23 US disclosed
CN-110072950-A For manufacturing the solder mask ink jet of printed circuit board 爱克发-格法特公司 2019-07-30 CN disclosed
CN-105452322-A Curable epoxy resin composition and cured product thereof, diene compound and method for producing same, and method for producing diepoxy compound DAICEL CORP 2016-03-30 CN disclosed
US-7220881-B2 Process for production of acid anhydride TOKUYAMA CORPORATION (JP) 2007-05-22 US disclosed
CN-1847221-A Process for preparing optionally substituted arylsulphonic anhydrides LANXESS DEUTSCHLAND GMBH (DE) 2006-10-18 CN disclosed
CN-1243723-C N-phenylpropylcyclopentyl substituted glutaramide derivatives as NEP inhibitors of FSAD PFIZER LTD (US) 2006-03-01 CN disclosed
CN-1220676-C Method for producing acid anhydride TOKUYAMA CORP (JP) 2005-09-28 CN disclosed
CN-1668662-A Solid polymer electrolyte NIPPON SODA CO (JP) 2005-09-14 CN disclosed
US-20040242929-A1 Process for production of acid anhydride TOKUYAMA CORPORATION (JP) 2004-12-02 US disclosed
CN-1537097-A Method for producing acid anhydride ��ʽ�����ɽ 2004-10-13 CN disclosed
EP-1413572-A1 PROCESS FOR PRODUCING ACID ANHYDRIDE Tokuyama Corporation (JP) 2004-04-28 EP disclosed
CN-1492852-A N-phenylpropylcyclopentyl substituted glutaramide derivatives as NEP inhibitors of FSAD ������ҩ�����޹�˾ 2004-04-28 CN disclosed
CN-1131940-A Hydrogenation PFIZER RES & DEV (IE) 1996-09-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231749-A1 Polyethylene Glycol Derivative And Preparation Method Thereof SI, RPS27A, PGF TSHR 4007/4885ACHE 4678/4885RAPGEF4 1587/4885
US-11168180-B2 Polyethylene glycol derivative and preparation method thereof SI, RPS27A, PGF TSHR 4007/4885ACHE 4678/4885RAPGEF4 1587/4885
US-20040242929-A1 Process for production of acid anhydride CA4, CA9, CA6 TSHR 565/4885ACHE 1515/4885RAPGEF4 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.