Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 7/20 | 0.50 |
| ▸ | CA2 known ✓ | P00918 | 7/20 | 0.50 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.37 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914417 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| SCHEMBL6914183 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| Potassium Ion SCHEMBL5359880 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| SCHEMBL6918559 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| SCHEMBL6917025 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| SCHEMBL6918122 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| SCHEMBL6914177 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| SCHEMBL6916931 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| Zinc Ion SCHEMBL6913238 | 0.94 | CA1 (0.50) | CA1CA2LMNATDP1MMP1 | |
| SCHEMBL19953365 | 0.85 | LMNA (0.55) | CA1CA2LMNATDP1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365168-B1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2021-06-30 | — | — | EP | claimed |
| CN-108367529-B | Lightweight flame retardant thermoplastic structures | 施内勒公司 | 2021-02-05 | — | — | CN | claimed |
| US-20170113445-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC | 2017-04-27 | — | — | US | claimed |
| US-8975367-B2 | Polyphosphonate and copolyphosphonate additive mixtures | FRX POLYMERS, INC. (US) | 2015-03-10 | — | — | US | claimed |
| EP-4130152-A1 | GLASS-FIBER-CONTAINING FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED OBJECT | ADEKA CORPORATION (JP) | 2023-02-08 | — | — | EP | disclosed |
| CN-115362213-A | Flame-retardant polycarbonate resin composition containing glass fiber and molded article | 株式会社ADEKA | 2022-11-18 | — | — | CN | disclosed |
| EP-2623974-B1 | SENSOR, SENSOR SYSTEM, AND SENSOR MANUFACTURE PROCESS | PHC HOLDINGS CORP (JP) | 2022-02-16 | — | — | EP | disclosed |
| EP-3365168-B1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2021-06-30 | — | — | EP | disclosed |
| CN-108367529-B | Lightweight flame retardant thermoplastic structures | 施内勒公司 | 2021-02-05 | — | — | CN | disclosed |
| US-20200338873-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2020-10-29 | — | — | US | disclosed |
| US-10761045-B2 | Sensor, sensor system, method of manufacturing sensor, and method of measuring concentration of target substance | PHC HOLDINGS CORPORATION (JP) | 2020-09-01 | — | — | US | disclosed |
| US-20200080956-A1 | SENSOR, SENSOR SYSTEM, METHOD OF MANUFACTURING SENSOR, AND METHOD OF MEASURING CONCENTRATION OF TARGET SUBSTANCE | PHC HOLDINGS CORP (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-0103123-A1 | Flame retardant copolyester-carbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4391935-A | Flame retardant polycarbonate composition | GENERAL ELECTRIC COMPANY (US) | 1983-07-05 | — | — | US | disclosed |
| WO-1982002895-A1 | FLAME RETARDANT POLYESTER-CARBONATE COMPOSITIONS | GEN ELECTRIC (US) | 1982-09-02 | — | — | WO | disclosed |
| US-4251434-A | ORGANIC SALTS OF ALKALINE AND ALKALINE EARTH METALS | GENERAL ELECTRIC COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
| US-4220583-A | CONTAINING PARTIALLY FLUORINATED POLYOLEFIN AND ALKALI METAL SULFONATE | GENERAL ELECTRIC COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4197232-A | Flame retardant polycarbonate composition | GENERAL ELECTRIC COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4104253-A | HALOGENATED ORGANIC ALKALI OR ALKALINE EARTH METAL SALTS | GENERAL ELECTRIC COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-3971756-A | SILOXANE, ORGANIC ALKALI OR ALKALINE EARTH SALTS | GENERAL ELECTRIC COMPANY (US) | 1976-07-27 | — | — | US | disclosed |