Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509017 | 0.89 | ACHE (0.34) | ACHE | |
| SCHEMBL10754442 | 0.88 | ACHE (0.37) | ACHE | |
| SCHEMBL10751317 | 0.85 | ACHE (0.32) | ACHE | |
| SCHEMBL10748964 | 0.85 | ACHE (0.32) | ACHE | |
| SCHEMBL263454 | 0.85 | KDM4E (0.32) | ACHE | |
| SCHEMBL514781 | 0.84 | KDM4E (0.31) | ACHE | |
| SCHEMBL10753643 | 0.83 | ACHE (0.34) | ACHE | |
| SCHEMBL9396624 | 0.83 | KDM4E (0.31) | — | |
| SCHEMBL12094903 | 0.82 | KDM4E (0.34) | ACHE | |
| SCHEMBL10754192 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146461-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-03-13 | — | — | EP | claimed |
| EP-3802080-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-07-19 | — | — | EP | claimed |
| EP-3976362-B1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-06-07 | — | — | EP | claimed |
| EP-3802081-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-03-01 | — | — | EP | claimed |
| US-11584097-B2 | Method for making opaque colored silicone hydrogel contact lenses | ALCON INC. (CH) | 2023-02-21 | — | — | US | claimed |
| US-20210347929-A1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2021-11-11 | — | — | US | claimed |
| EP-3052534-B1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2019-05-01 | — | — | EP | claimed |
| EP-2513711-B1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2017-07-12 | — | — | EP | claimed |
| EP-2598937-B1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2016-06-29 | — | — | EP | claimed |
| US-9341744-B2 | Amphiphilic polysiloxane prepolymers and uses thereof | NOVARTIS AG (CH) | 2016-05-17 | — | — | US | claimed |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-02-02 | — | — | US | claimed |
| EP-2374031-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | Novartis AG (CH) | 2011-10-12 | — | — | EP | claimed |
| WO-2011075377-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011071790-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | NOVARTIS AG (CH) | 2011-06-16 | — | — | WO | claimed |
| US-20110140292-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | ALCON INC. (CH) | 2011-06-16 | — | — | US | claimed |
| US-20110133350-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | ALCON INC. (CH) | 2011-06-09 | — | — | US | claimed |
| WO-2010133680-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | claimed |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
| US-20100258961-A1 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2010-10-14 | — | — | US | claimed |
| WO-2010071691-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2010-06-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584097-B2 | Method for making opaque colored silicone hydrogel contact lenses | COIL, CRYAB, CRYAA | ACHE 3113/4885 |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | VCL, MACF1, CFL1 | ACHE 4362/4885 |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | PIGS, ELOVL1, HACD2 | ACHE 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.