Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | WNT3A | P56704 | 2/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26254861 | 0.91 | HSD17B3 (0.82) | HSD17B3KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL16552778 | 0.88 | KMT2A (0.83) | KMT2ASMN1; SMN2L3MBTL1GSK3BMEN1 | |
| SCHEMBL12939306 | 0.87 | NPC1 (0.57) | HSD17B3KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL4839086 | 0.87 | HSD17B3 (0.71) | HSD17B3KMT2AL3MBTL1GSK3BMEN1 | |
| SCHEMBL8525199 | 0.85 | HSD17B3 (0.72) | HSD17B3KMT2AL3MBTL1GSK3BSTS | |
| SCHEMBL14571009 | 0.84 | LMNA (0.52) | HSD17B3KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9419411 | 0.84 | KMT2A (0.69) | HSD17B3KMT2ASMN1; SMN2L3MBTL1GSK3B | |
| SCHEMBL2082766 | 0.84 | HSD17B3 (0.73) | HSD17B3KMT2AL3MBTL1GSK3BSTS | |
| SCHEMBL19047793 | 0.84 | HSD17B3 (0.73) | HSD17B3KMT2AL3MBTL1GSK3BSTS | |
| SCHEMBL8510520 | 0.84 | HSD17B3 (0.73) | HSD17B3KMT2AL3MBTL1GSK3BSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118807-A | Method for synthesizing aryl butanone by ligand-regulated nickel-catalyzed aryl cyclopropyl ketone ring-opening hydrogenation | 陕西师范大学 | 2024-12-13 | — | — | CN | disclosed |
| US-20230357218-A1 | N-FORMAMIDOPYRAZOLINE DERIVATIVE AS P2X3 RECEPTOR ANTAGONIST AND USE THEREOF | HANGZHOU WESTAN PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2023-11-09 | — | — | US | disclosed |
| CN-113574042-B | Bisphenol composition and polycarbonate resin | 三菱化学株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-113574041-B | Bisphenol production method and polycarbonate resin production method | 三菱化学株式会社 | 2023-10-13 | — | — | CN | disclosed |
| US-20230157996-A1 | SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF | Shenzhen Bay Laboratory (CN) | 2023-05-25 | — | — | US | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |
| US-20210154221-A1 | 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS AND PREPARATIONS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2021-05-27 | — | — | US | disclosed |
| EP-3518927-B1 | 1-PHENYLPROPANONE COMPOUNDS AND USE THEREOF | UNIV DEGLI STUDI PADOVA (IT) | 2020-08-12 | — | — | EP | disclosed |
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
| US-5220063-A | Reacting arylisonitrosoalkanone with hydrogen and acyl doner in presence of transition metal catalyst | HOECHST CELANESE CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| US-5198585-A | Catalytic hydrogenation of arylisonitrosoalkanone | HOECHST CELANESE CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| WO-1993001158-A1 | METHOD FOR THE PREPARATION OF ARYLKETOAMINES | HOECHST CELANESE CORPORATION (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5175368-A | Hydrogenating aryl alpha-oximinoalkyl ketones in aqueous medium containing hydrochlroic acid, recovering salt | HOECHST CELANESE CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0491557-A1 | Process for the preparation of arylalkylamines and substituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0481705-A1 | Process for the preparation of arylalkylamines and substituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1992-04-22 | — | — | EP | disclosed |
| US-5041669-A | Reacting alkyl aryl ketones with alkyl nitrites, extracting product, catalytically hydrogenating/reducing in nonaqueous acid mixture | HOECHST CELANESE CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| US-5012007-A | Method for producing 1-indanone derivatives | HOECHST CELANESE CORPORATION, A CORP. OF DE | 1991-04-30 | — | — | US | disclosed |
| EP-0421759-A2 | Method for producing 1-indanone derivatives | HOECHST CELANESE CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0382077-A2 | Diaryl-substituted heterocyclic compound, its preparation and medicaments and cosmetics made thereof | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154221-A1 | 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS AND PREPARATIONS THEREOF | HPRT1, SAMHD1, DUT | HSD17B3 888/4885KMT2A 1261/4885SMN1; SMN2 2676/4885 |
| US-20230157996-A1 | SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF | SSB, EBNA1BP2, PML | HSD17B3 4452/4885KMT2A 854/4885SMN1; SMN2 2894/4885 |
| US-20230357218-A1 | N-FORMAMIDOPYRAZOLINE DERIVATIVE AS P2X3 RECEPTOR ANTAGONIST AND USE THEREOF | P2RX3, P2RX4, P2RX7 | HSD17B3 2248/4885KMT2A 4166/4885SMN1; SMN2 2119/4885 |
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | HSD17B3 2490/4885KMT2A 1610/4885SMN1; SMN2 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.