SCHEMBL5079129

SCHEMBL5079129

CCCC(CCC(=O)CC#CI)OC(N)=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL228836 0.83 LMNA (0.31) CTSK
SCHEMBL17805629 0.77 CTSK (0.42) CTSK
SCHEMBL8463146 0.73 MAPT (0.33)
SCHEMBL1899745 0.73 LMNA (0.32)
SCHEMBL5357385 0.71 CTSK (0.39) CTSK
SCHEMBL10935542 0.70 CTSK (0.49) CTSK
SCHEMBL10581048 0.70 CTSK (0.38) CTSK
SCHEMBL223392 0.69 PRKCA (0.46) CTSK
SCHEMBL6112007 0.69 CTSK (0.44) CTSK
SCHEMBL5701793 0.68 CHRM1 (0.33) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3675809-B1 USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS BASF SE (DE) 2023-09-27 EP disclosed
US-10584134-B2 Use of physiological cooling active ingredients, and agents containing such active ingredients SYMRISE AG (DE) 2020-03-10 US disclosed
US-20180093997-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS SYMRISE AG (DE) 2018-04-05 US disclosed
US-9718839-B2 Use of physiological cooling active ingredients, and agents containing such active ingredients SYMRISE AG (DE) 2017-08-01 US disclosed
US-8999358-B2 Aqueous insecticidal compositions and the use thereof for protecting lignocellulose-containing materials BASF AKTIENGESELLSCHAFT (DE) 2015-04-07 US disclosed
US-20150086491-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS SYMRISE AG (DE) 2015-03-26 US disclosed
US-8927605-B2 Use of physiological cooling active ingredients, and agents containing such active ingredients SYMRISE AG (DE) 2015-01-06 US disclosed
US-20120263659-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS BASF SE (DE) 2012-10-18 US disclosed
US-20080138371-A1 Aqueous Insecticidal Compositions and the Use Thereof for Protecting Lignocellulose-Containing Materials BASF AKTIENGESELLSCHAFT (DE) 2008-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138371-A1 Aqueous Insecticidal Compositions and the Use Thereof for Protecting Lignocellulose-Containing Materials ELOVL3, C9, ELOVL1 CTSK 2812/4885
US-20150086491-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS TRPM8, TRPM7, TRPM2 CTSK 669/4885
US-10584134-B2 Use of physiological cooling active ingredients, and agents containing such active ingredients TRPM8, TRPM7, TRPM2 CTSK 669/4885
US-20180093997-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS TRPM8, TRPM7, TRPM2 CTSK 669/4885
US-20120263659-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS TRPM8, TRPM7, TRPM2 CTSK 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.