SCHEMBL508332

SCHEMBL508332

C=C(C)C1=NC(C)(Cc2ccccc2)C(=O)O1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.36
BACE1 P56817 1/20 0.35
ALDH1A1 P00352 2/20 0.32
GAA P10253 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
CTSG P08311 1/20 0.31
PRTN3 P24158 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KMT2A Q03164 1/20 0.31
MYC P01106 1/20 0.31
PIK3CD O00329 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7219255 0.80 ELANE (0.40) ELANEBACE1ALDH1A1GAACTSG
SCHEMBL7272506 0.80 ELANE (0.40) ELANEBACE1ALDH1A1GAACTSG
SCHEMBL11268643 0.76 ALDH1A1 (0.40) ELANEBACE1ALDH1A1GAANPSR1
SCHEMBL509095 0.76 CYP1A2 (0.33) BACE1ALDH1A1GAA
SCHEMBL508522 0.74 BACE1 (0.37) BACE1KMT2A
SCHEMBL19239774 0.71 RAB9A (0.36) ALDH1A1GAANPSR1KDM4EMAPT
SCHEMBL509227 0.71 SIRT2 (0.31)
SCHEMBL27462154 0.69 MYC (0.30) MYC
SCHEMBL8741931 0.65 AKT1 (0.34) ELANEALDH1A1NPSR1
SCHEMBL7220662 0.65 NPSR1 (0.41) ALDH1A1NPSR1KDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12285922-B2 Method for making photofunctional contact lenses ALCON INC. (CH) 2025-04-29 US claimed
US-12111443-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-10-08 US claimed
EP-4313567-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP claimed
EP-4304842-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
EP-4304843-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
US-11833771-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2023-12-05 US claimed
US-11825845-B2 Slippery liquid-infused porous surfaces that release hydrophilic and hydrophobic agents WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-11-28 US claimed
US-11807778-B2 Influence of partial side chain hydrolysis on the growth and morphology of reactive polymer multilayers fabricated using azlactone-functionalized polymers WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-07 US claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
EP-4158392-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-04-05 EP claimed
EP-0413551-B1 Stabilized polymeric dispersions MINNESOTA MINING & MFG (US) 1995-05-24 EP claimed
US-5408002-A Blending with thermoplastic polymers; medical diagnostic equipment MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US claimed
WO-1993025594-A1 SUPPORTS HAVING AZLACTONE-FUNCTIONAL SURFACES, ADDUCT SUPPORTS, AND METHODS OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-12-23 WO claimed
US-5262484-A Free radical grafting to addition polymers; surface treatment with nucleophilic agents; adhesion properties for binding, immobilizing proteins; immunoassay MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US claimed
US-5239013-A Nonlinear optically active polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-24 US claimed
US-5075352-A Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-24 US claimed
US-5013795-A Azlactone graft copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-07 US claimed
EP-0413551-A2 Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-20 EP claimed
US-4451619-A COPOLYMERIZING AN ALKENYLAZLACTONE, RING OPENING WITH NUCLEOPHILE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-05-29 US claimed
EP-0105666-A1 Method of hydrophilizing or hydrophobizing polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-04-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825845-B2 Slippery liquid-infused porous surfaces that release hydrophilic and hydrophobic agents CLPP, MSN, LIPA ELANE 261/4885BACE1 2192/4885ALDH1A1 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.