SCHEMBL5085679

SCHEMBL5085679

CC(C)(C)N[Si](C)(C)C1C(CC2CCCCC2)=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HTR5A P47898 1/20 0.31
USP2 O75604 1/20 0.31
CYP1A2 P05177 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
CYP2C9 P11712 1/20 0.31
DRD1 P21728 1/20 0.31
TBXA2R P21731 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
KCNH2 Q12809 1/20 0.31
PSEN1 P49768 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630825 0.80 LMNA (0.31)
SCHEMBL5088233 0.79
SCHEMBL7636902 0.78 LMNA (0.32)
SCHEMBL7567494 0.78 LMNA (0.34) CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL5654080 0.77
SCHEMBL5085686 0.77 LMNA (0.32) CYP2D6
SCHEMBL7632646 0.77 LMNA (0.31)
SCHEMBL16393781 0.77 USP2 (0.32) USP2CYP1A2HTR1AADRA2ACYP2D6
SCHEMBL5088191 0.75 P2RX7 (0.35)
SCHEMBL5085350 0.73 P2RX7 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487886-B1 SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2008-08-06 EP disclosed
US-7098356-B2 Substituted indenyl metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES INC. (US) 2006-08-29 US disclosed
US-20050143536-A1 Substituted indenyl metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2005-06-30 US disclosed
EP-1487886-A1 SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS Dow Global Technologies Inc. (US) 2004-12-22 EP disclosed
WO-2003078483-A1 SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2003-09-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143536-A1 Substituted indenyl metal complexes and polymerization process ORC3, SOD1, YAP1 RAB9A 4541/4885ALDH1A1 1611/4885HTR5A 2815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.