Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636902 | 0.89 | LMNA (0.32) | LMNATDP1 | |
| SCHEMBL7632646 | 0.88 | LMNA (0.31) | LMNA | |
| SCHEMBL7630825 | 0.86 | LMNA (0.31) | LMNA | |
| SCHEMBL5088233 | 0.84 | — | — | |
| SCHEMBL5085686 | 0.82 | LMNA (0.32) | LMNACYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL5654080 | 0.82 | — | — | |
| SCHEMBL5088191 | 0.80 | P2RX7 (0.35) | — | |
| SCHEMBL5085679 | 0.78 | RAB9A (0.32) | CYP2D6CYP2C9 | |
| SCHEMBL5085350 | 0.78 | P2RX7 (0.32) | — | |
| SCHEMBL6066254 | 0.78 | ALDH1A1 (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015462-B1 | BIMETALLIC COMPLEXES AND POLYMERIZATION CATALYSTS THEREFROM | DOW CHEMICAL CO (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6284698-B1 | CATALYST FOR ADDITION POLYMERS | THE DOW CHEMICAL COMPANY | 2001-09-04 | — | — | US | disclosed |
| US-6153776-A | ADDITION POLYMERIZATION CATALYST ACTIVATED BY COCATALYST | THE DOW CHEMICAL (US) | 2000-11-28 | — | — | US | disclosed |
| EP-1015462-A1 | BIMETALLIC COMPLEXES AND POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999014222-A1 | BIMETALLIC COMPLEXES AND POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |