SCHEMBL5085686

SCHEMBL5085686

CC(C)(C)N[Si](C)(C)C1C(Cc2ccccc2)=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
CYP2D6 P10635 1/20 0.32
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085350 0.90 P2RX7 (0.32)
SCHEMBL7630825 0.85 LMNA (0.31) LMNA
SCHEMBL5088233 0.83
SCHEMBL7567494 0.82 LMNA (0.34) LMNACYP2D6TSHR
SCHEMBL7636902 0.82 LMNA (0.32) LMNA
SCHEMBL5088191 0.82 P2RX7 (0.35)
Hydrochloric Acid SCHEMBL5654080 0.81
SCHEMBL7632646 0.81 LMNA (0.31) LMNA
SCHEMBL5085679 0.77 RAB9A (0.32) CYP2D6
SCHEMBL6066254 0.77 ALDH1A1 (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487886-B1 SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2008-08-06 EP disclosed
US-7098356-B2 Substituted indenyl metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES INC. (US) 2006-08-29 US disclosed
US-20050143536-A1 Substituted indenyl metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2005-06-30 US disclosed
EP-1487886-A1 SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS Dow Global Technologies Inc. (US) 2004-12-22 EP disclosed
WO-2003078483-A1 SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2003-09-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143536-A1 Substituted indenyl metal complexes and polymerization process ORC3, SOD1, YAP1 LMNA 3724/4885CYP2D6 2408/4885HPGD 2197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.