SCHEMBL7632646

SCHEMBL7632646

CCCC1=Cc2ccccc2C1[Si](C)(C)NC(C)(C)C.[Ti]

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636902 0.99 LMNA (0.32) LMNA
SCHEMBL7567494 0.88 LMNA (0.34) LMNA
SCHEMBL7630825 0.87 LMNA (0.31) LMNA
Hydrochloric Acid SCHEMBL5654080 0.84
SCHEMBL5088233 0.83
SCHEMBL5085686 0.81 LMNA (0.32) LMNA
SCHEMBL5088191 0.79 P2RX7 (0.35)
SCHEMBL3811480 0.79 ALDH1A1 (0.30) LMNA
SCHEMBL5085350 0.77 P2RX7 (0.32)
SCHEMBL5085679 0.77 RAB9A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874860-B1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS DOW CHEMICAL CO (US) 2002-11-13 EP disclosed