SCHEMBL7636902

SCHEMBL7636902

CCCC1=Cc2ccccc2C1[Si](C)(C)NC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7632646 0.99 LMNA (0.31) LMNA
SCHEMBL7567494 0.89 LMNA (0.34) LMNATDP1
SCHEMBL7630825 0.89 LMNA (0.31) LMNA
SCHEMBL5088233 0.84
SCHEMBL5085686 0.82 LMNA (0.32) LMNA
Hydrochloric Acid SCHEMBL5654080 0.82
SCHEMBL5088191 0.80 P2RX7 (0.35)
SCHEMBL5085679 0.78 RAB9A (0.32)
SCHEMBL5085350 0.78 P2RX7 (0.32)
SCHEMBL6066254 0.78 ALDH1A1 (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874860-B1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS DOW CHEMICAL CO (US) 2002-11-13 EP disclosed
US-6015868-A CATALYSIS OF HIGH TEMPERATURE, SOLUTION POLYMERIZATION WHICH YIELDS HIGH MOLECULAR WEIGHT OLEFIN POLYMERS, BY USING COORDINATION CATALYST MIXED WITH AN ACTIVATING COCATALYST, EFFICIENCY THE DOW CHEMICAL COMPANY (US) 2000-01-18 US disclosed
EP-0874860-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1998-11-04 EP disclosed
WO-1997015583-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1997-05-01 WO disclosed