Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799718 | 0.78 | METAP2 (0.39) | METAP2PLK1FABP4MAPT | |
| SCHEMBL2834374 | 0.73 | DPP4 (0.31) | FABP4 | |
| SCHEMBL2835353 | 0.71 | CYP3A4 (0.42) | MCL1PLK1PLK3MMP2KDM4E | |
| SCHEMBL20184233 | 0.71 | METAP2 (0.38) | METAP2FABP4MMP2KDM4EHSD17B10 | |
| SCHEMBL1671719 | 0.71 | CES2 (0.40) | METAP2 | |
| SCHEMBL18006678 | 0.69 | ALDH1A1 (0.42) | KDM4EMAPT | |
| SCHEMBL28013873 | 0.68 | TYR (0.39) | METAP2PLK1PLK3MAPTALOX15 | |
| SCHEMBL28347885 | 0.68 | LMNA (0.41) | KDM4EMAPT | |
| SCHEMBL24908622 | 0.68 | RIPK1 (0.41) | METAP2 | |
| SCHEMBL2835128 | 0.67 | FFAR1 (0.35) | METAP2FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442475-B2 | Cyanopyridone derivatives as liquid crystals | MERCK PATENT GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20060165916-A1 | Cyanopyridone derivatives as liquid crystals | MERCK PATENT GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1594842-A1 | CYANOPYRIDONE DERIVATIVES AS LIQUID CRYSTALS | MERCK PATENT GmbH (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074253-A1 | CYANOPYRIDONE DERIVATIVES AS LIQUID CRYSTALS | MERCK PATENT GMBH (DE) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165916-A1 | Cyanopyridone derivatives as liquid crystals | EPM2A, ACMSD, CSPP1 | BID 3679/4885MCL1 4559/4885BCL2L1 2644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.