SCHEMBL5117895

SCHEMBL5117895

C=C1OC(C)(C(C)C23CC4CC(CC(C4)C2)C3)OC1=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.35
SLC47A1 Q96FL8 1/20 0.35
HSD11B1 P28845 1/20 0.35
MAPT P10636 1/20 0.34
EPHX2 P34913 2/20 0.33
P2RX7 Q99572 1/20 0.33
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5117591 0.78 HSD11B1 (0.33) SLC22A2SLC47A1HSD11B1MAPTEPHX2
SCHEMBL5124668 0.73 HSD11B1 (0.32) HSD11B1
SCHEMBL5117663 0.67 HSD11B1 (0.33) HSD11B1EPHX2ALDH1A1
SCHEMBL677940 0.66 SLC22A2 (0.62) SLC22A2SLC47A1MAPTEPHX2NPC1
SCHEMBL5117899 0.66 EPHX2 (0.36) EPHX2P2RX7ALDH1A1
SCHEMBL5110098 0.65 HSD11B1 (0.37) HSD11B1ALDH1A1
SCHEMBL40513 0.62 SLC22A2 (0.56) SLC22A2SLC47A1MAPTEPHX2NPC1
SCHEMBL5110358 0.62 HSD11B1 (0.38) HSD11B1EPHX2P2RX7ALDH1A1
SCHEMBL5117003 0.62 HSD11B1 (0.33) HSD11B1
SCHEMBL5117595 0.61 MEN1 (0.35) HSD11B1MAPTEPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1447403-B1 5-METHYLENE-1,3-DIOXOLAN-4-ONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, POLYMERS OF THE DERIVATIVES, RESIST COMPOSITIONS, AND PATTERN FORMATION PROCESS MITSUBISHI RAYON CO (JP) 2016-02-03 EP disclosed
US-7316884-B2 5-methylene-1,3-dioxolan-4-one derivatives, process for their production, polymers of the derivatives, resist compositions, and pattern formation process MITSUBISHI RAYON CO., LTD. (JP) 2008-01-08 US disclosed
US-20040248031-A1 5-Methylene-1,3-dioxolan-4-one derivatives, process for their production, polymers of the derivatives, resist compositions, and pattern formation process MITSUBISHI CHEMICAL CORPORATION (JP) 2004-12-09 US disclosed
EP-1447403-A1 5-METHYLENE-1,3-DIOXOLAN-4-ONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, POLYMERS OF THE DERIVATIVES, RESIST COMPOSITIONS, AND PATTERN FORMATION PROCESS Mitsubishi Rayon Co., Ltd. (JP) 2004-08-18 EP disclosed