Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606667 | 0.80 | GPR35 (1.00) | GPR35ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL10993529 | 0.79 | GPR35 (0.61) | GPR35ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL17340892 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AHPGDTSHR | |
| SCHEMBL9578460 | 0.76 | ALDH1A1 (0.59) | GPR35ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL23657876 | 0.76 | KDM4E (0.76) | ALDH1A1NPC1RAB9AHPGDTSHR | |
| SCHEMBL6999797 | 0.72 | GPR35 (0.56) | GPR35ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL7461107 | 0.71 | KDM4E (0.68) | GPR35ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL12391942 | 0.71 | GPR35 (0.71) | GPR35ALDH1A1NPC1RAB9AHPGD | |
| Dibenzothiophene SCHEMBL8068874 | 0.71 | TSHR (0.61) | ALDH1A1RAB9AHPGDTSHRLMNA | |
| Dibenzothiophene SCHEMBL4378681 | 0.71 | GPR3 (0.88) | ALDH1A1NPC1RAB9AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572376-B2 | Ligand compound, transition metal compound, and catalyst composition comprising the transition metal compound | LG CHEM, LTD. | 2023-02-07 | — | — | US | disclosed |
| US-20210179643-A1 | Ligand Compound, Transition Metal Compound, and Catalyst Composition Comprising the Transition Metal Compound | LG CHEM, LTD. (KR) | 2021-06-17 | — | — | US | disclosed |
| US-10975110-B2 | Ligand compound, transition metal compound, and catalyst composition comprising the transition metal compound | LG CHEM, LTD. | 2021-04-13 | — | — | US | disclosed |
| EP-3154990-B1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING | UNIV HONG KONG (CN) | 2019-09-11 | — | — | EP | disclosed |
| US-20190263844-A1 | Ligand Compound, Transition Metal Compound, and Catalyst Composition Comprising the Transition Metal Compound | LG CHEM, LTD. (KR) | 2019-08-29 | — | — | US | disclosed |
| US-9708528-B2 | Robust photochromic compounds with silicon- or phosphorus-containing heterocyclic ring and the production thereof | THE UNIVERSITY OF HONG KONG (HK) | 2017-07-18 | — | — | US | disclosed |
| US-9708528-B2 | Robust photochromic compounds with silicon- or phosphorus-containing heterocyclic ring and the production thereof | THE UNIVERSITY OF HONG KONG (HK) | 2017-07-18 | — | — | US | disclosed |
| WO-2015188790-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND PRODUCTION THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2015-12-17 | — | — | WO | disclosed |
| US-20150361332-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2015-12-17 | — | — | US | disclosed |
| US-20150361332-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2015-12-17 | — | — | US | disclosed |
| EP-2477981-A1 | HETEROCYCLIC MGLU5 ANTAGONISTS | Recordati Ireland Limited (IE) | 2012-07-25 | — | — | EP | disclosed |
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572376-B2 | Ligand compound, transition metal compound, and catalyst composition comprising the transition metal compound | CAD, CD274, ZC3H11A | GPR35 1951/4885ALDH1A1 3894/4885NPC1 2928/4885 |
| US-20190263844-A1 | Ligand Compound, Transition Metal Compound, and Catalyst Composition Comprising the Transition Metal Compound | CAD, CD274, ZC3H11A | GPR35 1951/4885ALDH1A1 3894/4885NPC1 2928/4885 |
| US-20210179643-A1 | Ligand Compound, Transition Metal Compound, and Catalyst Composition Comprising the Transition Metal Compound | CAD, CD274, ZC3H11A | GPR35 1951/4885ALDH1A1 3894/4885NPC1 2928/4885 |
| US-20150361332-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF | CRY1, CRY2, P2RY10 | GPR35 1592/4885ALDH1A1 2747/4885NPC1 4841/4885 |
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | OPRM1, GRM5, OPRD1 | GPR35 73/4885ALDH1A1 2610/4885NPC1 4017/4885 |
| US-10975110-B2 | Ligand compound, transition metal compound, and catalyst composition comprising the transition metal compound | CAD, CD274, ZC3H11A | GPR35 1951/4885ALDH1A1 3894/4885NPC1 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.