Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368807 | 0.82 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1BCAT2PRKCZ | |
| SCHEMBL5138276 | 0.73 | LMNA (0.49) | MEN1KMT2AALDH1A1BCAT2PRKCZ | |
| SCHEMBL1799330 | 0.73 | KMT2A (0.69) | MEN1KMT2AALDH1A1BCAT2PRKCZ | |
| SCHEMBL6842022 | 0.72 | BCAT2 (0.63) | MEN1KMT2AALDH1A1BCAT2HPGD | |
| SCHEMBL2368666 | 0.71 | RAB9A (0.55) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28605859 | 0.71 | BCAT2 (0.59) | MEN1KMT2AALDH1A1BCAT2PRKCZ | |
| SCHEMBL975812 | 0.70 | BCAT2 (0.55) | MEN1KMT2AALDH1A1BCAT2HPGD | |
| SCHEMBL3453136 | 0.70 | BCAT2 (0.50) | MEN1KMT2AALDH1A1BCAT2HPGD | |
| SCHEMBL8188234 | 0.70 | KMT2A (0.65) | MEN1KMT2AALDH1A1BCAT2PRKCZ | |
| SCHEMBL3980970 | 0.70 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1BCAT2PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291853-B1 | THIENON COMPOUNDS | BASF Aktiengesellschaft (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4908437-A | Thien-2-one compounds with an alkylidene or imino group in the 5-position of the ring | BASF AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |
| EP-0291853-A2 | Thienon compounds | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | disclosed |