SCHEMBL450416

SCHEMBL450416

C[n+]1ccccc1-c1c2nc(c(-c3cccc[n+]3C)c3ccc([nH]3)c(-c3cccc[n+]3C)c3nc(c(-c4cccc[n+]4C)c4ccc1[nH]4)C=C3)C=C2

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.54
▸ TOP1 P11387 1/20 0.39
▸ CYCS P99999 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17668308 0.98 TERT (0.53) TERTTOP1CYCS
Hydrochloric Acid SCHEMBL2555721 0.98 TERT (0.53) TERTTOP1CYCS
Hydrochloric Acid SCHEMBL2553050 0.97 TERT (0.51) TERTTOP1CYCS
Hydrochloric Acid SCHEMBL2555716 0.97 TERT (0.52) TERTTOP1
Hydrochloric Acid SCHEMBL2553046 0.97 TERT (0.52) TERTTOP1
SCHEMBL4552175 0.93 TERT (0.58) TERTTOP1CYCS
SCHEMBL14999536 0.89 TERT (0.46) TERT
SCHEMBL4271237 0.89 TERT (0.46) TERT
SCHEMBL4263240 0.89 TERT (0.46) TERT
SCHEMBL15003039 0.89 TERT (0.46) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119564697-A Application of G four-chain ligand and entecavir combined medication in anti HBV infection 武汉大学 2025-03-07 — — CN disclosed
US-20240390328-A1 PHARMACEUTICAL COMPOSITION CONTAINING AS ACTIVE INGREDIENT COMPOUND CONJUGATED TO G4 STRUCTURES OF CORONAVIRUSES FOR PREVENTION OR TREATMENT OF CORONAVIRUS INFECTIOUS DISEASES Research & Business Foundation Sungkyunkwan University (KR) 2024-11-28 — — US disclosed
WO-2022060209-A1 PHARMACEUTICAL COMPOSITION CONTAINING AS ACTIVE INGREDIENT COMPOUND CONJUGATED TO G4 STRUCTURES OF CORONAVIRUSES FOR PREVENTION OR TREATMENT OF CORONAVIRUS INFECTIOUS DISEASES 성균관대학교산학협력단 2022-03-24 — — WO disclosed
EP-3431088-A1 MNTBAP FOR USE IN INDUCING A TRANSIENT IMMUNE TOLERANCE Paris Sciences et Lettres - Quartier Latin (FR) 2019-01-23 — — EP disclosed
US-8987245-B2 Composition and method for affecting obesity and related conditions PARKER JONATHAN R BRESTOFF (US) 2015-03-24 — — US disclosed
US-20140357610-A1 COMPOSITION AND METHOD FOR AFFECTING OBESITY AND RELATED CONDITIONS PARKER JONATHAN R BRESTOFF (US) 2014-12-04 — — US disclosed
US-20140243294-A1 METHOD OF ACTIVATION OF OXAZAPHOSPHORINES DUKE UNIVERSITY (US) 2014-08-28 — — US disclosed
US-8759324-B2 Method of activation of oxazaphosphorines DUKE UNIVERSITY (US) 2014-06-24 — — US disclosed
US-20130172296-A1 METHOD OF ACTIVATION OF OXAZAPHOSPHORINES UNIV DUKE (US) 2013-07-04 — — US disclosed
US-8399434-B2 Method of activation of oxazaphosphorines DUKE UNIVERSITY (US) 2013-03-19 — — US disclosed
WO-2008073195-A2 METHOD FOR ACTIVATION OF OXAZAPHOSPHORINES DUKE UNIVERSITY (US) 2008-06-19 — — WO disclosed
US-20080113956-A1 Substituted Porphyrins FRIDOVICH IRWIN 2008-05-15 — — US disclosed
US-20070179124-A1 Substituted Porphyrins FRIDOVICH IRWIN 2007-08-02 — — US disclosed
US-20060074062-A1 Substituted porphyrins DUKE UNIVERSITY (US) 2006-04-06 — — US disclosed
US-6916799-B2 Substituted porphyrins DUKE UNIVERSITY (US) 2005-07-12 — — US disclosed
US-20040058902-A1 Substituted porphyrins DUKE UNIVERSITY 2004-03-25 — — US disclosed
US-20040039211-A1 Tetrapyrroles DUKE UNIVERSITY AND NATIONAL JEWISH MEDICAL AND RESEARCH CENTER 2004-02-26 — — US disclosed
EP-1045851-B1 SUBSTITUTED PORPHYRINS UNIV DUKE (US) 2003-04-23 — — EP disclosed
US-20030069281-A1 Tetrapyrroles GOODNOW CAPITAL, L.L.C. 2003-04-10 — — US disclosed
US-20020042407-A1 Antiinflammatory agents; respiratory system disorders DUKE UNIVERSITY 2002-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113956-A1 Substituted Porphyrins PPOX, GPX4, PRDX5 TERT 821/4885TOP1 4291/4885CYCS 76/4885
US-20070179124-A1 Substituted Porphyrins PPOX, GPX4, PRDX5 TERT 821/4885TOP1 4291/4885CYCS 76/4885
US-20020042407-A1 Antiinflammatory agents; respiratory system disorders LPO, PRDX5, MPO TERT 3237/4885TOP1 4338/4885CYCS 265/4885
US-20060074062-A1 Substituted porphyrins PPOX, GPX4, PRDX5 TERT 821/4885TOP1 4291/4885CYCS 76/4885
US-20140243294-A1 METHOD OF ACTIVATION OF OXAZAPHOSPHORINES PPOX, HMBS, OAT TERT 3295/4885TOP1 1564/4885CYCS 888/4885
US-20040058902-A1 Substituted porphyrins SOD1, SOD3, CAT TERT 1933/4885TOP1 2957/4885CYCS 190/4885
US-20030069281-A1 Tetrapyrroles PPOX, TXNRD2, PRDX5 TERT 1022/4885TOP1 4311/4885CYCS 204/4885
US-20040039211-A1 Tetrapyrroles PPOX, TXNRD2, PRDX5 TERT 1022/4885TOP1 4311/4885CYCS 204/4885
US-20240390328-A1 PHARMACEUTICAL COMPOSITION CONTAINING AS ACTIVE INGREDIENT COMPOUND CONJUGATED TO G4 STRUCTURES OF CORONAVIRUSES FOR PREVENTION OR TREATMENT OF CORONAVIRUS INFECTIOUS DISEASES SARS1, GTF3C4, GTF3C5 TERT 3233/4885TOP1 708/4885CYCS 3757/4885
US-20130172296-A1 METHOD OF ACTIVATION OF OXAZAPHOSPHORINES PPOX, HMBS, OAT TERT 3295/4885TOP1 1564/4885CYCS 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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