Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477632 | 0.86 | MEN1 (0.33) | MEN1KMT2ACA14 | |
| SCHEMBL201046 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL3880970 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL79980 | 0.76 | ESR2 (0.52) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL819814 | 0.74 | CA1 (0.58) | ALDH1A1TDP1CYP3A4MAPK1MAPT | |
| SCHEMBL2602434 | 0.74 | ACHE (0.48) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL626870 | 0.74 | LMNA (0.42) | ALDH1A1CYP3A4TSHRMAOAMAPT | |
| SCHEMBL121643 | 0.74 | NFE2L2 (0.37) | ALDH1A1MAOAMAOBAPPL3MBTL1 | |
| SCHEMBL819491 | 0.74 | CYP2A6 (0.42) | ALDH1A1TSHRMAPK1MAOAMAPT | |
| SCHEMBL18670944 | 0.74 | NFE2L2 (0.37) | ALDH1A1MAOAMAOBAPPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249719-A | Long-acting stable near-infrared cell membrane targeting probe and preparation thereof | 中山大学附属第八医院（深圳福田） | 2022-03-29 | — | — | CN | claimed |
| US-20070141678-A1 | Processes for purifying oligosaccharides | THE PROCTER & GAMBLE COMPANY | 2007-06-21 | — | — | US | claimed |
| US-11858952-B2 | Compound and color conversion film comprising same | LG CHEM, LTD. (KR) | 2024-01-02 | — | — | US | disclosed |
| US-20230227458-A1 | IRREVERSIBLE INHIBITORS OF MENIN-MLL INTERACTION | BIOMEA FUSION, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20230226195-A1 | TARGETED ABERRANT ALPHA-SYNUCLEIN SPECIES AND INDUCED UBIQUITINATION AND PROTEOSOMAL CLEARANCE VIA CO-RECRUITMENT OF AN E3-LIGASE SYSTEM | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| US-11702421-B2 | Substituted pyridines as irreversible inhibitors of menin-MLL interaction | BIOMEA FUSION, LLC (US) | 2023-07-18 | — | — | US | disclosed |
| WO-2023109883-A1 | AROMATIC HETEROCYCLE-SUBSTITUTED COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |
| CN-115894538-A | Preparation method of folic acid coupled boron-containing compound | 安徽普利药业有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114983940-A | Bioactive nano micelle and synthesis method thereof | 汉中职业技术学院 | 2022-09-02 | — | — | CN | disclosed |
| WO-2022166610-A1 | PYRIDAZINONE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-08-11 | — | — | WO | disclosed |
| US-9926314-B2 | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG (CH) | 2018-03-27 | — | — | US | disclosed |
| US-20150011522-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | IRM LLC (BM) | 2015-01-08 | — | — | US | disclosed |
| US-8871754-B2 | Compounds and compositions for the treatment of parasitic diseases | IRM LLC (BM) | 2014-10-28 | — | — | US | disclosed |
| US-20140243366-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-8754219-B2 | Compounds that modulate intracellular calcium | CALCIMEDICA, INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20140155367-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2014-06-05 | — | — | US | disclosed |
| US-20130203818-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20110166132-A1 | Gamma Secretase Modulators | AMGEN INC. (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110118234-A1 | Urea Compounds as Gamma Secretase Modulators | AMGEN INC. | 2011-05-19 | — | — | US | disclosed |
| US-20070141678-A1 | Processes for purifying oligosaccharides | THE PROCTER & GAMBLE COMPANY | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118234-A1 | Urea Compounds as Gamma Secretase Modulators | BACE1, BACE2, PSEN1 | ALDH1A1 2026/4885TDP1 1020/4885CYP3A4 2272/4885 |
| US-20230227458-A1 | IRREVERSIBLE INHIBITORS OF MENIN-MLL INTERACTION | MLLT1, MEN1, MLLT3 | ALDH1A1 4440/4885TDP1 3269/4885CYP3A4 4547/4885 |
| US-11702421-B2 | Substituted pyridines as irreversible inhibitors of menin-MLL interaction | MLLT1, MEN1, MLLT3 | ALDH1A1 4225/4885TDP1 3497/4885CYP3A4 4062/4885 |
| US-20150011522-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | MAPT, CYP11B1, CYP11B2 | ALDH1A1 1143/4885TDP1 4186/4885CYP3A4 213/4885 |
| US-20140243366-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | ALDH1A1 4409/4885TDP1 3096/4885CYP3A4 4329/4885 |
| US-20130203818-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | ALDH1A1 4409/4885TDP1 3096/4885CYP3A4 4329/4885 |
| US-20140155367-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | MAPT, CYP11B1, CYP11B2 | ALDH1A1 1143/4885TDP1 4186/4885CYP3A4 213/4885 |
| US-20110166132-A1 | Gamma Secretase Modulators | BACE1, BACE2, PSEN1 | ALDH1A1 3262/4885TDP1 782/4885CYP3A4 3765/4885 |
| US-11858952-B2 | Compound and color conversion film comprising same | BLVRB, CDYL, CRY1 | ALDH1A1 689/4885TDP1 3493/4885CYP3A4 385/4885 |
| US-20230226195-A1 | TARGETED ABERRANT ALPHA-SYNUCLEIN SPECIES AND INDUCED UBIQUITINATION AND PROTEOSOMAL CLEARANCE VIA CO-RECRUITMENT OF AN E3-LIGASE SYSTEM | SNCA, ADRM1, UBE3C | ALDH1A1 3075/4885TDP1 1645/4885CYP3A4 4301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.