Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592804 | 0.87 | CCR1 (0.59) | CCR1CCR5CCR8TRPA1NPC1 | |
| SCHEMBL13985936 | 0.85 | CCR1 (0.66) | CCR1CCR5CCR8TRPA1CHRNA7 | |
| SCHEMBL13950331 | 0.83 | KMO (0.46) | CCR1CCR5CCR8KMONPC1 | |
| SCHEMBL9569010 | 0.82 | CCR1 (0.53) | CCR1CCR5CCR8TRPA1AMY1A | |
| SCHEMBL29445848 | 0.81 | KMO (0.54) | TRPA1KMONPC1RAB9ATGFBR1 | |
| SCHEMBL19072696 | 0.81 | KMO (0.54) | TRPA1KMONPC1RAB9ATGFBR1 | |
| SCHEMBL27322683 | 0.80 | CCR1 (0.63) | CCR1CCR5CCR8TRPA1CHRNA7 | |
| SCHEMBL9538699 | 0.80 | CCR1 (0.50) | CCR1CCR5CCR8TRPA1CHRNA7 | |
| SCHEMBL14280366 | 0.79 | TRPA1 (0.45) | CCR1CCR5CCR8TRPA1CHRNA7 | |
| SCHEMBL12828417 | 0.78 | CCR1 (0.56) | CCR1CCR5CCR8CHRNA7AMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2023-05-23 | — | — | US | disclosed |
| US-20210002269-A1 | COMPOUNDS | STEP PHARMA S.A.S. (FR) | 2021-01-07 | — | — | US | disclosed |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3109238-B1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | UNIV SOUTHERN CALIFORNIA (US) | 2019-09-18 | — | — | EP | disclosed |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2018-01-18 | — | — | US | disclosed |
| EP-1966343-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH TRIAZOLES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |
| US-9583720-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-28 | — | — | US | disclosed |
| EP-3109238-A1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | University of Southern California (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-2062908-B1 | Transition metal complexes comprising pyrazolylcarbazole ligands | UNIV SOUTHERN CALIFORNIA (US) | 2016-07-13 | — | — | EP | disclosed |
| US-7338722-B2 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |
| US-7166368-B2 | Electroluminescent platinum compounds and devices made with such compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-01-23 | — | — | US | disclosed |
| US-20050233234-A1 | Electroluminescent platinum compounds and devices made with such compounds | LECLOUX DANIEL D | 2005-10-20 | — | — | US | disclosed |
| US-6858327-B2 | Organic light emitting materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2004-12-16 | — | — | US | disclosed |
| EP-1442095-A1 | ELECTROLUMINESCENT PLATINUM COMPOUNDS AND DEVICES MADE WITH SUCH COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2004045001-A2 | ORGANIC LIGHT EMITTING MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20040091738-A1 | Organic light emitting materials and devices | UNIVERSAL DISPLAY CORPORATION | 2004-05-13 | — | — | US | disclosed |
| US-20030108771-A1 | Electroluminescent platinum compounds and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY | 2003-06-12 | — | — | US | disclosed |
| WO-2003040257-A1 | ELECTROLUMINESCENT PLATINUM COMPOUNDS AND DEVICES MADE WITH SUCH COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | CTPS1, CTPS2, TBXAS1 | CCR1 4747/4885CCR5 4713/4885CCR8 4837/4885 |
| US-20050233234-A1 | Electroluminescent platinum compounds and devices made with such compounds | PMS2, PARG, PAX2 | CCR1 3449/4885CCR5 2012/4885CCR8 2436/4885 |
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | NR2E3, IK, NR2C2 | CCR1 988/4885CCR5 823/4885CCR8 1957/4885 |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | EML4, RCOR3, CPNE4 | CCR1 2249/4885CCR5 3026/4885CCR8 2069/4885 |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | EML4, AFF4, RCOR3 | CCR1 2588/4885CCR5 3017/4885CCR8 2515/4885 |
| US-20210002269-A1 | COMPOUNDS | UGT1A1, CYP1A1, CYP19A1 | CCR1 878/4885CCR5 1779/4885CCR8 1558/4885 |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | EML4, AFF4, RCOR3 | CCR1 2588/4885CCR5 3017/4885CCR8 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.