SCHEMBL5161331

SCHEMBL5161331

NS(=O)(=O)C(CC(=O)[O-])C(=O)[O-].[Na+].[Na+]

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA4 known ✓ P22748 3/20 0.44
CA2 known ✓ P00918 1/20 0.41
CTSL P07711 1/20 0.38
CPT2 P23786 1/20 0.33
CPT1A P50416 1/20 0.33
SLC22A16 Q86VW1 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187912 0.79 CA4 (0.46) CA4CA2CTSLCPT2CPT1A
SCHEMBL28695498 0.79 CA4 (0.46) CA4CA2CTSLCPT2CPT1A
SCHEMBL740787 0.79 CA4 (0.46) CA4CA2CTSLCPT2CPT1A
Methylamine SCHEMBL9540584 0.78 CA2 (0.43) CA4CA2CTSLCPT2CPT1A
SCHEMBL29914627 0.77 CA4 (0.44) CA4CA2CTSLSLC22A16CASP1
SCHEMBL29240278 0.77 CA4 (0.44) CA4CA2CTSLSLC22A16CASP1
Potassium Ion SCHEMBL28948988 0.77 CA4 (0.44) CA4CA2CTSLSLC22A16CASP1
Water SCHEMBL18893639 0.77 CA4 (0.44) CA4CA2CTSLSLC22A16CASP1
Fluoride SCHEMBL31332593 0.77 CA4 (0.44) CA4CA2CTSLSLC22A16CASP1
Ethylenediamine SCHEMBL10844557 0.77 CA4 (0.40) CA4CA2CTSLCPT2CPT1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021261388-A1 LIQUID AGROCHEMICAL COMPOSITION 三井化学アグロ株式会社 2021-12-30 WO disclosed
EP-1356928-B1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2007-02-14 EP disclosed
US-20030211418-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2003-11-13 US disclosed
EP-1356928-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-10-29 EP disclosed