SCHEMBL5162463

SCHEMBL5162463

O=S(=O)(Cl)c1cccc(C(F)(F)F)c1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SLC22A12 Q96S37 9/20 0.39
RXFP1 Q9HBX9 1/20 0.37
HSD11B1 P28845 2/20 0.36
CES1 P23141 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SLC40A1 Q9NP59 1/20 0.35
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP2C9 P11712 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35
SLC22A11 Q9NSA0 1/20 0.35
KAT6A Q92794 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7368671 0.84 MEN1 (0.41) TRPV4MEN1KMT2ASLC22A12RXFP1
SCHEMBL29500393 0.82 MEN1 (0.56) TRPV4MEN1KMT2ASLC22A12RXFP1
SCHEMBL65955 0.82 MEN1 (0.56) TRPV4MEN1KMT2ASLC22A12RXFP1
SCHEMBL17850502 0.81 TRPV4 (0.44) TRPV4MEN1KMT2ASLC22A12RXFP1
SCHEMBL6240708 0.81 CCR4 (0.44) TRPV4MEN1KMT2ASLC22A12RXFP1
SCHEMBL29434897 0.81 CCR4 (0.44) TRPV4MEN1KMT2ASLC22A12RXFP1
SCHEMBL6254835 0.81 HSD11B1 (0.40) TRPV4MEN1KMT2ASLC22A12HSD11B1
SCHEMBL2512044 0.81 CA2 (0.46) MEN1KMT2ASLC22A12CYP2C9
SCHEMBL30681743 0.81 SLC22A12 (0.39) TRPV4MEN1KMT2ASLC22A12HSD11B1
SCHEMBL3062954 0.81 MEN1 (0.43) MEN1KMT2ASLC22A12HSD11B1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250174718-A1 GEL ELECTROLYTE COMPOSITION AND SECONDARY BATTERY INCLUDING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-05-29 US disclosed
CN-118786552-A Gel electrolyte composition and secondary battery comprising same 韩国化学研究院 2024-10-15 CN disclosed
WO-2023128366-A1 GEL ELECTROLYTE COMPOSITION AND SECONDARY BATTERY COMPRISING SAME 한국화학연구원 2023-07-06 WO disclosed
EP-2718264-B1 BENZOCYCLOHEPTENE ACETIC ACIDS HOFFMANN LA ROCHE (CH) 2015-08-05 EP disclosed
EP-2718264-A1 BENZOCYCLOHEPTENE ACETIC ACIDS F.HOFFMANN-LA ROCHE AG (CH) 2014-04-16 EP disclosed
WO-2012168162-A1 BENZOCYCLOHEPTENE ACETIC ACIDS F. HOFFMANN-LA ROCHE AG (CH) 2012-12-13 WO disclosed
US-20120309796-A1 BENZOCYCLOHEPTENE ACETIC ACIDS FIROOZNIA FARIBORZ (US) 2012-12-06 US disclosed
EP-1763361-A2 STEROID SPARING AGENTS AND THEIR USE Elan Pharmaceuticals, Inc. (US) 2007-03-21 EP disclosed
WO-2005097162-A2 STEROID SPARING AGENTS AND THEIR USE ELAN PHARMACEUTICALS, INC. (US) 2005-10-20 WO disclosed
EP-1185261-A4 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORP (US) 2004-02-25 EP disclosed
EP-1185261-A1 IL-8 RECEPTOR ANTAGONISTS SmithKline Beecham Corporation (US) 2002-03-13 EP disclosed
WO-2000076495-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2000-12-21 WO disclosed
EP-0799198-B1 ANTI-INFLAMMATORY COMPOUNDS SMITHKLINE BEECHAM CORP (US) 2000-08-30 EP disclosed
EP-0799198-A4 1997-10-15 EP disclosed
EP-0799198-A1 ANTI-INFLAMMATORY COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1997-10-08 EP disclosed
US-5545669-A Anti-inflammatory compounds SMITHKLINE BEECHAM CORPORATION 1996-08-13 US disclosed
WO-1995033461-A1 ANTI-INFLAMMATORY COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1995-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309796-A1 BENZOCYCLOHEPTENE ACETIC ACIDS ACAT2, ACAT1, CYP27A1 TRPV4 2291/4885MEN1 4369/4885KMT2A 2259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.