Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631691 | 0.85 | RAB9A (0.74) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL374022 | 0.85 | RAB9A (0.74) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL6081315 | 0.78 | CYP19A1 (0.60) | CHEK1CYP19A1ITKESR1 | |
| SCHEMBL6081220 | 0.78 | MEN1 (0.60) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL935681 | 0.77 | KDR (0.65) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL5053299 | 0.74 | NPC1 (0.87) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL5051826 | 0.74 | KDR (0.68) | RAB9ANPC1KDM4EMAPTMEN1 | |
| Phosphoric Acid SCHEMBL7651467 | 0.73 | RAB9A (0.59) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL7194943 | 0.73 | KDR (0.56) | RAB9ANPC1KDM4EMAPTMEN1 | |
| Methane SCHEMBL28704887 | 0.72 | KDR (0.66) | RAB9ANPC1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619391-B | Heterocyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2022-08-05 | — | — | CN | claimed |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | claimed |
| EP-1275646-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-01-15 | — | — | EP | claimed |
| CN-112533930-B | Organometallic complexes, polymers, mixtures, compositions, and organic electronic devices comprising the same | 广州华睿光电材料有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-112533930-A | Organometallic complexes, polymers containing the same, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-111051982-A | Organic EL display device and method for forming pixel division layer and planarization layer | 东丽株式会社 | 2020-04-21 | — | — | CN | disclosed |
| US-20070299125-A1 | Substituted indoles | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070299126-A1 | Substituted pyrrole-indoles | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| US-7268159-B2 | Substituted indoles | WYETH (US) | 2007-09-11 | — | — | US | disclosed |
| US-7265148-B2 | Substituted pyrrole-indoles | WYETH (US) | 2007-09-04 | — | — | US | disclosed |
| EP-1682530-B1 | PYRROLE SUBSTITUTED INDOLES AS INHIBITORS OF PAI-1 | WYETH CORP (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20050113439-A1 | Substituted pyrrole-indoles | WYETH (US) | 2005-05-26 | — | — | US | disclosed |
| US-20050113438-A1 | Substituted indoles | WYETH (US) | 2005-05-26 | — | — | US | disclosed |
| WO-2005030756-A1 | SUBSTITUTED PYRROLE-INDOLES AS INHIBITORS OF PAI-1 | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005030717-A1 | SUBSTITUTED INDOLE ACID DERIVATIVES AND THEIR USE AS PAI-1 INHIBITORS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
| EP-1275646-A4 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEM RES (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | disclosed |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | disclosed |
| EP-1275646-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001074807-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113439-A1 | Substituted pyrrole-indoles | IDO2, IDO1, TPH2 | RAB9A 2975/4885NPC1 4362/4885KDM4E 486/4885 |
| US-20070299126-A1 | Substituted pyrrole-indoles | IDO2, IDO1, TPH2 | RAB9A 2975/4885NPC1 4362/4885KDM4E 486/4885 |
| US-20070299125-A1 | Substituted indoles | IDO2, IDO1, INMT | RAB9A 3184/4885NPC1 2685/4885KDM4E 1399/4885 |
| US-20050113438-A1 | Substituted indoles | IDO2, IDO1, INMT | RAB9A 3184/4885NPC1 2685/4885KDM4E 1399/4885 |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | AIFM1, BAX, CASP3 | RAB9A 2626/4885NPC1 1080/4885KDM4E 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.