Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11102406 | 0.97 | — | — | |
| SCHEMBL11872377 | 0.93 | CASP1 (0.53) | — | |
| Lithium Ion SCHEMBL11507581 | 0.93 | — | — | |
| Water SCHEMBL11506403 | 0.90 | — | — | |
| Fluoroacetate SCHEMBL288372 | 0.77 | — | — | |
| Fluoroacetate SCHEMBL30106705 | 0.77 | — | — | |
| Fluoroacetate SCHEMBL226060 | 0.77 | — | — | |
| Fluoroacetate SCHEMBL32663020 | 0.74 | CASP1 (0.92) | — | |
| Fluoroacetate SCHEMBL9620166 | 0.74 | — | — | |
| Fluoroacetate SCHEMBL27420325 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117185971-A | Method for synthesizing florfenicol by coupling through chemical enzyme method | 福州大学 | 2023-12-08 | — | — | CN | claimed |
| CN-116375615-A | Preparation method of florfenicol amine, intermediate thereof and preparation method thereof | 弈柯莱生物科技(上海)股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-117185971-B | Method for synthesizing florfenicol by coupling through chemical enzyme method | 福州大学 | 2025-11-18 | — | — | CN | disclosed |
| US-20240360131-A1 | BIARYL KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2024-10-31 | — | — | US | disclosed |
| US-12065437-B2 | Biaryl kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-20 | — | — | US | disclosed |
| CN-117305376-A | Method for synthesizing sesquiterpene by regulating and controlling glucose metabolism of escherichia coli | 江南大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-117185971-A | Method for synthesizing florfenicol by coupling through chemical enzyme method | 福州大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-117185971-A | Method for synthesizing florfenicol by coupling through chemical enzyme method | 福州大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-116375615-A | Preparation method of florfenicol amine, intermediate thereof and preparation method thereof | 弈柯莱生物科技(上海)股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-20210277001-A1 | BIARYL KINASE INHIBITORS | Cosmic Pet LLC | 2021-09-09 | — | — | US | disclosed |
| US-10981910-B2 | Biaryl kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-20 | — | — | US | disclosed |
| US-20060058383-A1 | Propyl 3-bromo-2-oxopropionate and derivatives as novel anticancer agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-03-16 | — | — | US | disclosed |
| WO-2006020403-A2 | 3-HALO-2-OXOPROPIONATE SALTS AND ESTERS AS NOVEL ANTICANCER AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-02-23 | — | — | WO | disclosed |
| EP-0173497-B1 | TETRACYCLIC SPIRO-HYDANTOIN ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4656169-A | ENZYME INHIBITORS | PFIZER INC. (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0173497-A1 | Tetracyclic spiro-hydantoin aldose reductase inhibitors | PFIZER INC. (US) | 1986-03-05 | — | — | EP | disclosed |
| WO-1986001107-A1 | TETRACYCLIC SPIRO-HYDANTOIN ALDOSE REDUCTASE INHIBITORS, COMPOSITIONS AND METHODS OF MAKING | PFIZER INC. (US) | 1986-02-27 | — | — | WO | disclosed |
| US-4149012-A | Synthesis of racemic 3-fluoro-alanine and its salts | MERCK & CO., INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-3976689-A | Process for preparing 3-fluoro-D-alanine and its deutero analogs | MERCK & CO., INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3972921-A | Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts | MERCK & CO., INC. (US) | 1976-08-03 | — | — | US | disclosed |