Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SDCBP | O00560 | 1/20 | 0.42 |
| ▸ | SDC2 | P34741 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175236 | 0.85 | ALDH1A1 (0.53) | TYRECE1MMECTSLCTSB | |
| SCHEMBL6148841 | 0.80 | ADAMTS4 (0.53) | TYRECE1MMECTSLCTSB | |
| SCHEMBL1287168 | 0.80 | CTSL (0.63) | ECE1MMECTSLCTSBCTSS | |
| SCHEMBL2978398 | 0.80 | CTSL (0.63) | ECE1MMECTSLCTSBCTSS | |
| SCHEMBL8671882 | 0.80 | CTSL (0.63) | ECE1MMECTSLCTSBCTSS | |
| SCHEMBL220569 | 0.80 | CTSL (0.63) | ECE1MMECTSLCTSBCTSS | |
| SCHEMBL19607509 | 0.79 | CTSL (0.55) | TYRECE1MMECTSLCTSB | |
| SCHEMBL6150990 | 0.79 | TSHR (0.60) | TYRECE1MMECTSLCTSB | |
| SCHEMBL10801663 | 0.78 | TYR (0.49) | TYRECE1MMECTSLCTSB | |
| SCHEMBL8744811 | 0.78 | SDCBP (0.51) | TSHRALDH1A1SDCBPSDC2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177168-B1 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA INC (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20040116355-A1 | Caspase inhibitors and the use thereof | CYTOVIA, INC. | 2004-06-17 | — | — | US | disclosed |
| US-6716818-B2 | DIPEPTIDE DERIVATIVES | CYTOVIA, INC. | 2004-04-06 | — | — | US | disclosed |
| EP-1177168-A4 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA INC (US) | 2003-06-25 | — | — | EP | disclosed |
| US-20020058631-A1 | Caspase inhibitors and the use thereof | CYTOVIA, INC. | 2002-05-16 | — | — | US | disclosed |
| US-6355618-B1 | ENZYME INHIBITORS | CYTOVIA, INC. | 2002-03-12 | — | — | US | disclosed |
| EP-1177168-A1 | CASPASE INHIBITORS AND THE USE THEREOF | Cytovia, Inc. (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000061542-A1 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2000-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058631-A1 | Caspase inhibitors and the use thereof | CASP1, CASP3, CASP10 | TYR 3867/4885ECE1 243/4885MME 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.