SCHEMBL6783180

SCHEMBL6783180

NCCN1CCC(CO)CC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.52
PRMT3 O60678 1/20 0.50
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
PRMT1 Q99873 1/20 0.50
PRMT8 Q9NR22 1/20 0.50
GNAO1 P09471 3/20 0.47
GNAI3 P08754 2/20 0.47
GNAI1 P63096 2/20 0.47
LTA4H P09960 1/20 0.40
NCF1 P14598 1/20 0.38
ACHE P22303 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
CHRM3 P20309 1/20 0.35
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
SLC18A3 Q16572 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
ACE2 Q9BYF1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL9345651 0.90 PRMT3 (0.47) ALOX15PRMT3CARM1PRMT6PRMT1
SCHEMBL25344529 0.87 ARG1 (0.43) ALOX15PRMT3CARM1PRMT6PRMT1
SCHEMBL10064775 0.87 ARG1 (0.43) ALOX15PRMT3CARM1PRMT6PRMT1
SCHEMBL10064196 0.87 ARG1 (0.43) ALOX15PRMT3CARM1PRMT6PRMT1
SCHEMBL9332530 0.87 KEAP1 (0.47) ALOX15PRMT3CARM1PRMT6PRMT1
SCHEMBL598481 0.83 ALOX15 (0.48) ALOX15PRMT3CARM1PRMT6PRMT1
SCHEMBL13569909 0.81 NCF1 (0.58) ALOX15PRMT3CARM1PRMT6PRMT1
SCHEMBL1316226 0.81 SLC18A3 (0.47) GNAO1LTA4HACHEHRH3SLC18A3
Hydrochloric Acid SCHEMBL598795 0.81 GNAO1 (0.47) ALOX15PRMT3CARM1PRMT6PRMT1
Oxalic Acid SCHEMBL9344962 0.79 CHRM3 (0.41) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115199828-B Corrosion-resistant metal hose for underground pipeline connection and construction method thereof 青岛亿联建设集团股份有限公司 2023-08-08 CN claimed
CN-115199828-A Corrosion-resistant metal hose for underground pipeline connection and construction method thereof 青岛亿联建设集团股份有限公司 2022-10-18 CN claimed
CN-113801292-B Water dispersion of polyurethane or polyurethane urea and preparation method thereof, water-based space leather base and preparation method thereof 万华化学集团股份有限公司 2022-08-05 CN claimed
CN-113801292-A Aqueous dispersion of polyurethane or polyurethane urea and preparation method thereof, aqueous space leather base and preparation method thereof 万华化学集团股份有限公司 2021-12-17 CN claimed
US-12528948-B2 Amino (meth)acrylates ALLNEX BELGIUM S.A. (BE) 2026-01-20 US disclosed
US-12084445-B2 Broad-spectrum carbapenems VenatoRx Pharmaceuticals, Inc. (US) 2024-09-10 US disclosed
US-20240109917-A1 PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS ACTELION PHARMACEUTICALS LTD (CH) 2024-04-04 US disclosed
EP-4267585-A1 PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS Actelion Pharmaceuticals Ltd (CH) 2023-11-01 EP disclosed
CN-116802184-A Pyrazolothiazole carboxamides and their use as PDGFR inhibitors 埃科特莱茵药品有限公司 2023-09-22 CN disclosed
CN-115199828-B Corrosion-resistant metal hose for underground pipeline connection and construction method thereof 青岛亿联建设集团股份有限公司 2023-08-08 CN disclosed
US-20230151222-A1 AMINO (METH)ACRYLATES ALLNEX BELGIUM S.A. (BE) 2023-05-18 US disclosed
WO-2023067125-A1 OLIGOSACCHARIDE COMPLEXES AND USES BioNTech SE (DE) 2023-04-27 WO disclosed
EP-0885190-B1 N-SUBSTITUTED 4-((4'-AMINOBENZOYL)-OXYMETHYL)-PIPERIDINES HAVING GASTRIC PROKINETIC PROPERTIES JANSSEN PHARMACEUTICA NV (BE) 2003-05-07 EP disclosed
US-6509339-B2 Gastrointestinal disorders; cardiovascular disorders JANSSEN PHARMACEUTICA N.V. (BE) 2003-01-21 US disclosed
US-20020042430-A1 Novel esters of 1, 4-disubstituted piperidine derivatives BOSMANS JEAN-PAUL RENE MARIE (BE) 2002-04-11 US disclosed
US-6291481-B1 CONDITIONS RELATED TO A HAMPERED OR IMPAIRED GASTRIC EMPTYING AND MORE GENERALLY TO TREAT CONDITIONS RELATED TO A HAMPERED OR IMPAIRED GASTROINTESTINAL TRANSIT. JANSSEN PHARMACEUTICA, N.V. (BE) 2001-09-18 US disclosed
EP-0885190-A1 NOVEL N-SUBSTITUTED 4-((4'-AMINOBENZOYL)-OXYMETHYL)-PIPERIDINES HAVING GASTRIC PROKINETIC PROPERTIES JANSSEN PHARMACEUTICA N.V. (BE) 1998-12-23 EP disclosed
WO-1997031897-A1 NOVEL N-SUBSTITUTED 4-((4'-AMINOBENZOYL)-OXYMETHYL)-PIPERIDINES HAVING GASTRIC PROKINETIC PROPERTIES JANSSEN PHARMACEUTICA N.V. (BE) 1997-09-04 WO disclosed
EP-0366004-B1 Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof BOEHRINGER MANNHEIM GMBH (DE) 1994-03-30 EP disclosed
EP-0366004-A1 Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof Roche Diagnostics GmbH (DE) 1990-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042430-A1 Novel esters of 1, 4-disubstituted piperidine derivatives CBR1, ALK, ESRRA ALOX15 222/4885PRMT3 837/4885CARM1 614/4885
US-12528948-B2 Amino (meth)acrylates MAT2B, MAT1A, MMAB ALOX15 3780/4885PRMT3 109/4885CARM1 134/4885
US-20240109917-A1 PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS PDGFRA, PDGFRB, ABL1 ALOX15 3144/4885PRMT3 1957/4885CARM1 2342/4885
US-12084445-B2 Broad-spectrum carbapenems MGAM, ALPI, SI ALOX15 2739/4885PRMT3 2805/4885CARM1 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.