SCHEMBL51892

SCHEMBL51892

CCCCOC(=O)c1cccc2c(=O)c3ccccc3sc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.57
TDP1 Q9NUW8 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
MAPK1 P28482 3/20 0.52
CYP3A4 P08684 2/20 0.52
TP53 P04637 1/20 0.52
ALDH1A1 P00352 9/20 0.51
HSD17B10 Q99714 2/20 0.51
LMNA P02545 2/20 0.51
KDM4E B2RXH2 4/20 0.49
POLB P06746 1/20 0.46
MAPT P10636 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAOB P27338 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
KDM4A O75164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29456921 1.00 TSHR (0.57) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL28837381 0.87 TSHR (0.53) TSHRL3MBTL1ALDH1A1HSD17B10LMNA
SCHEMBL10731867 0.87 TSHR (0.50) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL22960674 0.86 TSHR (0.43) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL23361692 0.86 ALDH1A1 (0.43) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL6245881 0.85 TSHR (0.57) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL1830507 0.85 ALDH1A1 (0.43) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL27636711 0.83 TSHR (0.52) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL9124986 0.83 ALDH1A1 (0.52) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL9332290 0.82 TSHR (0.39) TSHRTDP1L3MBTL1MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 851 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265607-A1 Treatment Liquid Composition, Set Of Ink Jet Ink Composition And Treatment Liquid Composition, And Treatment Method SEIKO EPSON CORPORATION (JP) 2023-08-24 US claimed
US-11535979-B2 Fiber material for cement reinforcement TEIJIN LIMITED (JP) 2022-12-27 US claimed
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN claimed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US claimed
EP-3248954-B1 CEMENT OR MORTAR FORMED BODY COMPRISING CEMENT-REINFORCING FIBER MATERIAL TEIJIN LTD (JP) 2020-02-19 EP claimed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US claimed
US-20190046463-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME ICURE PHARMACEUTICAL INC. (KR) 2019-02-14 US claimed
EP-3415141-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME Icure Pharmaceutical Inc. (KR) 2018-12-19 EP claimed
CN-101802022-B Photoinitiators for energy curing LAMBERTI SPA 2013-03-27 CN claimed
EP-2190887-B1 PHOTOINITIATORS FOR ENERGY CURING LAMBERTI SPA (IT) 2011-05-04 EP claimed
CN-101802022-A Photoinitiators for energy curing LAMBERTI SPA 2010-08-11 CN claimed
US-20100196826-A1 Photoinitiators for Energy Curing LAMBERTI SPA (IT) 2010-08-05 US claimed
EP-2190887-A1 PHOTOINITIATORS FOR ENERGY CURING Lamberti Spa (IT) 2010-06-02 EP claimed
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US claimed
EP-2121323-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS Lamberti Spa (IT) 2009-11-25 EP claimed
WO-2009037130-A1 PHOTOINITIATORS FOR ENERGY CURING LAMBERTI SPA (IT) 2009-03-26 WO claimed
WO-2008104436-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS LAMBERTI SPA (IT) 2008-09-04 WO claimed
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set RESONAC CORPORATION (JP) 2026-05-26 US disclosed
EP-0152377-A2 Curable compositions and their use CIBA-GEIGY AG (CH) 1985-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set ESD, CDH1, ASH2L TSHR 2827/4885TDP1 2103/4885L3MBTL1 2458/4885
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX TSHR 3231/4885TDP1 440/4885L3MBTL1 3770/4885
US-20100196826-A1 Photoinitiators for Energy Curing PPOX, ECPAS, PTGES TSHR 4756/4885TDP1 1570/4885L3MBTL1 3345/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH TSHR 4176/4885TDP1 549/4885L3MBTL1 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.