SCHEMBL519379

SCHEMBL519379

O=C(OCc1ccccc1)N1CCN(C2CCNCC2)CC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.60
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
CYP2C19 P33261 1/20 0.57
TMEM97 Q5BJF2 6/20 0.54
SIGMAR1 Q99720 6/20 0.54
HTR1A P08908 2/20 0.54
HRH2 P25021 2/20 0.54
HRH1 P35367 2/20 0.54
HRH3 Q9Y5N1 2/20 0.54
ADRA2C P18825 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
HTR2C P28335 2/20 0.52
CHRM4 P08173 1/20 0.52
CHRM5 P08912 1/20 0.52
ADRA2A P08913 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL310185 0.93 SMN1; SMN2 (0.53) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL26099888 0.93 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL589097 0.93 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL1206723 0.90 SMN1; SMN2 (0.64) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL30602898 0.89 SMN1; SMN2 (0.51) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL30602906 0.89 SMN1; SMN2 (0.51) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL27162521 0.88 SMN1; SMN2 (0.53) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
Hydrochloric Acid SCHEMBL29198425 0.87 SMN1; SMN2 (0.52) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL13636153 0.87 SIGMAR1 (0.65) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97
SCHEMBL693066 0.87 SMN1; SMN2 (0.59) SMN1; SMN2NPC1RAB9ACYP2C19TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026103846-A1 CYCLIC COMPOUND AND PREPARATION THEREFOR AND PHARMACEUTICAL USE THEREOF 山东先声再明生物制药有限公司 2026-05-21 WO disclosed
EP-4624466-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 EP disclosed
US-20240383874-A1 BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. 2024-11-21 US disclosed
US-20240317711-A1 AURKA SELECTIVE DEGRADATION INDUCING COMPOUND UPPTHERA INC. (KR) 2024-09-26 US disclosed
US-20240269298-A1 PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-08-15 US disclosed
WO-2024112119-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 WO disclosed
EP-4332100-A1 PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-03-06 EP disclosed
CN-117425646-A Phosphono derivative, composition thereof and pharmaceutical application thereof 西藏海思科制药有限公司 2024-01-19 CN disclosed
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H BIOTECH INC. (KR) 2023-10-12 US disclosed
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H BIOTECH INC. (KR) 2023-10-12 US disclosed
US-7595312-B2 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2009-09-29 US disclosed
US-7595312-B2 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2009-09-29 US disclosed
US-20080319188-A1 Novel pyridine derivatives and pyrimidine derivatives (3) EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-12-25 US disclosed
US-20080319188-A1 Novel pyridine derivatives and pyrimidine derivatives (3) EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-12-25 US disclosed
US-20080319188-A1 Novel pyridine derivatives and pyrimidine derivatives (3) EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-12-25 US disclosed
US-20080300242-A1 Imidazopyridine Kinase Inhibitors GLAXOSMITHKLINE LLC 2008-12-04 US disclosed
US-20080300242-A1 Imidazopyridine Kinase Inhibitors GLAXOSMITHKLINE LLC 2008-12-04 US disclosed
CN-101198590-A Novel pyridine derivative and pyrimidine derivative (3) EISAI R&D MAN CO LTD (JP) 2008-06-11 CN disclosed
EP-1889836-A1 NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3) Eisai R&D Management Co., Ltd. (JP) 2008-02-20 EP disclosed
US-20060079504-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) 2006-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240269298-A1 PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF EGFR, BLK, CSNK1A1L SMN1; SMN2 4694/4885NPC1 1807/4885RAB9A 1068/4885
US-20080300242-A1 Imidazopyridine Kinase Inhibitors ABL1, MAP3K19, MAP3K5 SMN1; SMN2 2982/4885NPC1 2713/4885RAB9A 1901/4885
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF EGFR, KRAS, ERBB2 SMN1; SMN2 4518/4885NPC1 1220/4885RAB9A 468/4885
US-20240383874-A1 BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF AR, SF3B5, SF3B1 SMN1; SMN2 884/4885NPC1 933/4885RAB9A 1759/4885
US-20080319188-A1 Novel pyridine derivatives and pyrimidine derivatives (3) HGF, MET, FLT4 SMN1; SMN2 4771/4885NPC1 2775/4885RAB9A 425/4885
US-20060079504-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions CALCRL, CALCR, CALCA SMN1; SMN2 4092/4885NPC1 1479/4885RAB9A 1956/4885
US-20240317711-A1 AURKA SELECTIVE DEGRADATION INDUCING COMPOUND STUB1, AURKA, XIAP SMN1; SMN2 3705/4885NPC1 1360/4885RAB9A 2559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.