Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201529 | 0.85 | NR1H2 (0.43) | USP30UCHL1GPR119GRM5 | |
| SCHEMBL5203615 | 0.83 | UCHL1 (0.38) | USP30UCHL1GPR119GRM5CHEK2 | |
| SCHEMBL5202192 | 0.81 | UCHL1 (0.37) | USP30UCHL1GPR119GRM5CHEK2 | |
| SCHEMBL3568596 | 0.78 | NOS2 (0.39) | GPR119GRM5 | |
| SCHEMBL5200864 | 0.74 | ADORA2A (0.33) | — | |
| SCHEMBL5204446 | 0.69 | HCRTR1 (0.37) | USP30UCHL1GRM5 | |
| SCHEMBL30563583 | 0.68 | GPR119 (0.41) | USP30UCHL1GPR119L3MBTL1 | |
| SCHEMBL5200295 | 0.67 | HRH3 (0.39) | USP30UCHL1ACACB | |
| SCHEMBL30563646 | 0.66 | PKM (0.46) | GPR119L3MBTL1 | |
| SCHEMBL20807473 | 0.65 | ALDH1A1 (0.44) | GPR119L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817030-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | Kalypsys, Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060424-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | KALYPSYS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |