Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202266 | 0.96 | CACNA1G (0.42) | CACNA1GHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL5203921 | 0.91 | CNR1 (0.43) | ALDH1A1GAAHSD17B10KCNH2 | |
| SCHEMBL5203925 | 0.87 | CNR1 (0.43) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL5201971 | 0.81 | CACNA1G (0.44) | CACNA1GCCR3OPRM1ALDH1A1GAA | |
| SCHEMBL5204629 | 0.81 | SIGMAR1 (0.48) | CACNA1GHTR2AOPRM1ALDH1A1GAA | |
| SCHEMBL5201178 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GAAHSD17B10KCNH2 | |
| SCHEMBL5201976 | 0.77 | OPRM1 (0.43) | CACNA1GCCR3OPRM1ALDH1A1GAA | |
| SCHEMBL5204633 | 0.77 | SIGMAR1 (0.46) | CACNA1GOPRM1ALDH1A1GAAHSD17B10 | |
| SCHEMBL5201928 | 0.75 | SIGMAR1 (0.47) | OPRM1ALDH1A1GAAHSD17B10 | |
| SCHEMBL5201180 | 0.74 | KDM1A (0.42) | OPRM1ALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |