Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204633 | 0.95 | SIGMAR1 (0.46) | SIGMAR1CACNA1GALDH1A1GAAHSD17B10 | |
| SCHEMBL5201928 | 0.89 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1GAAHSD17B10OPRM1 | |
| SCHEMBL5201931 | 0.85 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1GAAHSD17B10OPRM1 | |
| SCHEMBL5202261 | 0.81 | CACNA1G (0.44) | CACNA1GALDH1A1GAAHSD17B10OPRM1 | |
| SCHEMBL5201971 | 0.78 | CACNA1G (0.44) | SIGMAR1CACNA1GALDH1A1GAAHSD17B10 | |
| SCHEMBL5202266 | 0.77 | CACNA1G (0.42) | SIGMAR1CACNA1GALDH1A1GAAHSD17B10 | |
| SCHEMBL5203921 | 0.75 | CNR1 (0.43) | SIGMAR1ALDH1A1GAAHSD17B10 | |
| SCHEMBL5201178 | 0.75 | ALDH1A1 (0.44) | SIGMAR1ALDH1A1GAAHSD17B10 | |
| SCHEMBL5201976 | 0.74 | OPRM1 (0.43) | SIGMAR1CACNA1GALDH1A1GAAHSD17B10 | |
| SCHEMBL8609753 | 0.74 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1GAAHSD17B10OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |