SCHEMBL522134

SCHEMBL522134

CCN1C(=O)C2C3C=CC(C3)C2C1=O

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.66
KMT2A Q03164 3/20 0.63
RAB9A P51151 2/20 0.63
MEN1 O00255 2/20 0.63
SMN1; SMN2 Q16637 4/20 0.61
HTT P42858 3/20 0.61
LMNA P02545 1/20 0.61
KDM4E B2RXH2 3/20 0.61
L3MBTL1 Q9Y468 1/20 0.59
TSHR P16473 2/20 0.58
USP2 O75604 1/20 0.58
HSD17B10 Q99714 1/20 0.58
MAPK1 P28482 2/20 0.56
TDP1 Q9NUW8 1/20 0.55
PKM P14618 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C19 P33261 1/20 0.54
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21729686 1.00 ALDH1A1 (0.66) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL17470589 1.00 ALDH1A1 (0.66) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL20022939 0.87 ALDH1A1 (0.56) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL5862604 0.84 ALDH1A1 (0.72) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL14344292 0.83 ALDH1A1 (0.84) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL10022041 0.83 ALDH1A1 (0.70) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL13528565 0.83 ALDH1A1 (0.84) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL11529889 0.81 ALDH1A1 (0.79) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL11594277 0.80 ALDH1A1 (0.83) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL28513627 0.80 ALDH1A1 (0.56) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US claimed
US-11725077-B2 Olefin metathesis photopolymers PolySpectra, Inc. (US) 2023-08-15 US disclosed
CN-108885398-B Radiation-sensitive resin composition and electronic component 日本瑞翁株式会社 2022-11-29 CN disclosed
US-20210386861-A1 BRUSH PRODRUGS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-12-16 US disclosed
US-20210317143-A9 BORONIC ESTER PRODRUGS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2021-10-14 US disclosed
US-20210284664-A1 DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-09-16 US disclosed
US-20210220391-A1 PROTEOLYSIS TARGETING CHIMERIC MOLECULES (PROTACS) WITH FUNCTIONAL HANDLES AND USES THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-07-22 US disclosed
US-20210163676-A1 OLEFIN METATHESIS PHOTOPOLYMERS NATIONAL SCIENCE FOUNDATION 2021-06-03 US disclosed
US-20200399414-A1 Self-Assembled Elastomers with Molecularly Encoded Tissue-Like Softness, Strain-Adaptive Stiffening and Coloration THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2020-12-24 US disclosed
US-20200369685-A1 BORONIC ESTER PRODRUGS AND USES THEREOF MASSACHUSETTS INST TECHNOLOGY (US) 2020-11-26 US disclosed
US-7365229-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-04-29 US disclosed
US-20080081902-A1 PURIFICATION OF SYNTHETIC OLIGOMERS MICHIGAN TECHNOLOGICAL UNIVERSITY 2008-04-03 US disclosed
US-7271227-B1 Adhesive compositions free of metallic catalyst HENKEL CORPORATION (US) 2007-09-18 US disclosed
US-4150137-A ANTIINFLAMMATORY, ANTIPYRETIC, AND ANALGESIC AGENTS HISAMITSU PHARMACEUTICAL CO. INC. (JP) 1979-04-17 US disclosed
US-4105608-A HIGH IMPACT COMPOSITION OF RING-OPENING POLYMERIZATION PRODUCT SHOWA DENKO K.K. (JP) 1978-08-08 US disclosed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US disclosed
US-4059561-A AND A HALOGEN COMPOUND SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed
US-4022954-A ADHESIVES, FLOCCULATING AGENTS, ION EXCHANGE RESINS, MOLDING AGENTS SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-05-10 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3959234-A CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210386861-A1 BRUSH PRODRUGS AND USES THEREOF ABCB11, SI, ABCB1 ALDH1A1 789/4885KMT2A 2639/4885RAB9A 2169/4885
US-20200369685-A1 BORONIC ESTER PRODRUGS AND USES THEREOF BRCA1, BTD, BCHE ALDH1A1 731/4885KMT2A 2907/4885RAB9A 2312/4885
US-20210284664-A1 DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF SI, ILK, PCNA ALDH1A1 2604/4885KMT2A 2882/4885RAB9A 3208/4885
US-20210220391-A1 PROTEOLYSIS TARGETING CHIMERIC MOLECULES (PROTACS) WITH FUNCTIONAL HANDLES AND USES THEREOF CRBN, PSMA6, PSMA3 ALDH1A1 3287/4885KMT2A 2978/4885RAB9A 3151/4885
US-20210317143-A9 BORONIC ESTER PRODRUGS AND USES THEREOF BRCA1, BTD, BCHE ALDH1A1 731/4885KMT2A 2907/4885RAB9A 2312/4885
US-20080081902-A1 PURIFICATION OF SYNTHETIC OLIGOMERS RNGTT, NOP2, CAPZA2 ALDH1A1 4461/4885KMT2A 3324/4885RAB9A 3916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.