SCHEMBL52243

SCHEMBL52243

COCCOC(=O)c1ccc2c(=O)c3ccccc3sc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 5/20 0.46
RAB9A P51151 3/20 0.46
MAPT P10636 3/20 0.46
NPC1 O15118 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 2/20 0.46
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TP53 P04637 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
MEN1 O00255 1/20 0.40
HCRTR1 O43613 1/20 0.40
KMT2A Q03164 1/20 0.40
GABRP O00591 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29456885 1.00 KDM4E (0.46) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL19612305 0.92 ALDH1A1 (0.47) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL10989791 0.86 ALDH1A1 (0.54) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL22960674 0.85 TSHR (0.43) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL10993897 0.85 KDM4E (0.36) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL490194 0.84 MAPT (0.52) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL16569803 0.81 ALDH1A1 (0.42) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL31544285 0.81 TSHR (0.43) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL5030843 0.81 ALDH1A1 (0.50) KDM4EALDH1A1RAB9AMAPTNPC1
SCHEMBL20016206 0.80 ESR1 (0.43) KDM4EALDH1A1RAB9AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 834 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN claimed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US claimed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US claimed
US-20190046463-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME ICURE PHARMACEUTICAL INC. (KR) 2019-02-14 US claimed
EP-3415141-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME Icure Pharmaceutical Inc. (KR) 2018-12-19 EP claimed
CN-108697657-A Ultraviolet-curable hydrogel resin for transdermal administration, hydrogel, and poultice containing same Icure药品株式会社 2018-10-23 CN claimed
CN-101802022-B Photoinitiators for energy curing LAMBERTI SPA 2013-03-27 CN claimed
EP-2190887-B1 PHOTOINITIATORS FOR ENERGY CURING LAMBERTI SPA (IT) 2011-05-04 EP claimed
CN-101802022-A Photoinitiators for energy curing LAMBERTI SPA 2010-08-11 CN claimed
US-20100196826-A1 Photoinitiators for Energy Curing LAMBERTI SPA (IT) 2010-08-05 US claimed
EP-2190887-A1 PHOTOINITIATORS FOR ENERGY CURING Lamberti Spa (IT) 2010-06-02 EP claimed
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US claimed
CN-101646564-A Hydroxamates as photoinitiators LAMBERTI SPA IT 2010-02-10 CN claimed
EP-2121323-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS Lamberti Spa (IT) 2009-11-25 EP claimed
WO-2009037130-A1 PHOTOINITIATORS FOR ENERGY CURING LAMBERTI SPA (IT) 2009-03-26 WO claimed
WO-2008104436-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS LAMBERTI SPA (IT) 2008-09-04 WO claimed
EP-0138754-A2 Photocurable compositions CIBA-GEIGY AG (CH) 1985-04-24 EP claimed
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set RESONAC CORPORATION (JP) 2026-05-26 US disclosed
US-4506083-A INITIATORS FOR PHOTOPOLYMERIZATION OR PHOTOCHEMICAL CROSSLINKING CIBA-GEIGY CORPORATION (US) 1985-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set ESD, CDH1, ASH2L KDM4E 2247/4885ALDH1A1 95/4885RAB9A 4022/4885
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX KDM4E 2292/4885ALDH1A1 262/4885RAB9A 3269/4885
US-20100196826-A1 Photoinitiators for Energy Curing PPOX, ECPAS, PTGES KDM4E 1954/4885ALDH1A1 434/4885RAB9A 3210/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH KDM4E 1292/4885ALDH1A1 179/4885RAB9A 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.