Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232312 | 0.84 | ABL1 (0.32) | ABL1DYRK1AWNT1TRPV1 | |
| SCHEMBL5235809 | 0.82 | MAPT (0.44) | — | |
| SCHEMBL5239098 | 0.81 | MEN1 (0.39) | — | |
| SCHEMBL5235901 | 0.81 | ABL1 (0.37) | ABL1DYRK1AWNT1TRPV1GSK3B | |
| SCHEMBL5236743 | 0.80 | ALDH1A1 (0.45) | — | |
| SCHEMBL5236419 | 0.80 | ADAMTS5 (0.39) | — | |
| SCHEMBL5233364 | 0.79 | MAPT (0.39) | — | |
| SCHEMBL5231485 | 0.79 | HTR3A (0.44) | TRPV1 | |
| SCHEMBL5236354 | 0.79 | CHRNB2 (0.38) | — | |
| SCHEMBL5235446 | 0.78 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |